{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T00:40:50Z","timestamp":1793234450133,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,6,6]],"date-time":"2023-06-06T00:00:00Z","timestamp":1686009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study was carried out to assess the effects of omega\u20103 supplementation as an adjunct treatment for eating and psychological symptoms in patients with anorexia nervosa.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a systematic review of the literature using the terms \u2018anorexia nervosa\u2019 AND \u2018Fatty Acids, Omega\u20103\u2019. Five randomised controlled trials with a total of 144 participants, published between 2003 and 2022, were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The effects of supplementation of omega\u20103 on anxiety were standardised mean difference (SMD) 0.79, 95% confidence interval (CI) \u22120.08 to 1.66;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.08;\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u20093%; two studies, 33 participants; moderate quality of evidence. For depression, the supplementation of omega\u20103 was SMD: 0.22, 95% CI: \u22120.50 to 0.93;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.18;\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u200945%; two studies, 33 participants; moderate quality of evidence. For obsessive\u2010compulsive disorder, the supplementation of omega\u20103 was SMD: \u22120.22, 95% CI: \u22120.70 to 2.25;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.36;\n                      <jats:italic>I<\/jats:italic>\n                      \u00b2\u2009=\u20090%; three studies, 32 participants; low quality of evidence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This research showed that regardless of dose, time or, if associated with other components, the use of omega\u20103 supplementations as an adjuvant treatment showed no evidence of effect in eating and psychological symptoms in patients with anorexia nervosa.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.13187","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T05:48:54Z","timestamp":1684993734000},"page":"1970-1981","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Omega\u20103 as an adjuvant in the treatment eating and psychological symptoms in patients with anorexia nervosa: a systematic review and meta\u2010analyses"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3080-3309","authenticated-orcid":false,"given":"Ana Claudia Rodrigues","family":"Candido","sequence":"first","affiliation":[{"name":"Translational Biomedicine Laboratory, Graduate Program in Health Sciences University of Southern Santa Catarina (UNESC) Crici\u00fama SC Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah Dagostin","family":"Ferraz","sequence":"additional","affiliation":[{"name":"Translational Biomedicine 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