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Advances in treatment protocols have resulted in survival rates of &gt;80% in most high\u2010income countries (HIC); however, children and young people (CYP) with ALL continue to face significant nutrition\u2010related challenges during treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This narrative review outlines the changing landscape of treatment and survivorship for CYP with ALL and the advances in nutrition knowledge that call for changes to clinical nutrition practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The incidence of ALL has remained stable in HIC; however, there have been significant advances in survival over the past 30 years. Overweight and obesity are increasingly prevalent in CYP with ALL at diagnosis, during treatment and in survivorship. Coupled with poor diet quality, high\u2010energy and saturated fat intakes, altered eating behaviours and inactivity, this necessitates the need for a shift in nutrition intervention. Undernutrition remains a concern for CYP with high\u2010risk treatment protocols where oral or enteral nutrition support remains a cornerstone of maintaining nutrition status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>With improved treatment protocols and high survival rates, a shift to focusing on diet quality, prevention of excessive weight gain and obesity during treatment and survivorship is necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.13273","type":"journal-article","created":{"date-parts":[[2024,1,8]],"date-time":"2024-01-08T01:14:21Z","timestamp":1704676461000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The evolution of nutritional care in children and young people with acute lymphoblastic leukaemia: a narrative review"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1708-9633","authenticated-orcid":false,"given":"Amy L.","family":"Lovell","sequence":"first","affiliation":[{"name":"Department of Nutrition and Dietetics, The University of Auckland Faculty of Medical and Health Sciences Auckland New Zealand"},{"name":"Starship Blood and Cancer Centre Starship Child Health Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8700-9643","authenticated-orcid":false,"given":"Breeana","family":"Gardiner","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Great Ormond Street Hospital NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Henry","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Dietetics Royal Marsden NHS Foundation Trust Surrey UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica M.","family":"Bate","sequence":"additional","affiliation":[{"name":"Department of Paediatric Oncology Southampton Children's Hospital Southampton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark F. 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