{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:39:38Z","timestamp":1789479578373,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T00:00:00Z","timestamp":1729036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Blended tube feeds are reported to be better tolerated in some children compared to standard commercial enteral formulas, allowing children to normalise feeding by having similar foods as the rest of the family. However, a blended tube feed is contraindicated in patients who are immunocompromised or require post\u2010pyloric feeding as a result of a food safety risk. Other contraindications for blended diet include children who require continuous pump feeding via gastrostomy or nasogastric feeding tube (&lt; 12 Fr) and fluid restrictions. To meet the demands of consumers, manufacturers have developed enteral formulas with food\u2010derived ingredients (EFI). Commercially available EFIs are relatively novel in the UK. The present study aimed to monitor the implementation of an EFI by dietitians in a specialist children's hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A single\u2010centre retrospective study was conducted to monitor the dietetic practice of commencing a commercially available EFI (Compleat\u00ae\u202fpaediatric; Nestl\u00e9 Health Science; 1.2\u2009kcal\/ml with 14% food\u2010derived ingredients). Using electronic medical notes, data were collected on all children who commenced an EFI via an enteral feeding tube in a specialist paediatric hospital between August 2022 and December 2023. Data were gathered on demographics (age, sex and primary diagnosis), anthropometric measurements (weight\u2010for\u2010age\n                      <jats:italic>Z<\/jats:italic>\n                      \u2010score and height\u2010for\u2010age\n                      <jats:italic>Z<\/jats:italic>\n                      \u2010score), feed regimens (feed volume, feeding route, mode of feeding [continuous, bolus]), gastrointestinal symptoms (gastro\u2010oesophageal reflux, vomiting, abdominal discomfort, constipation and loose stools) and geographical discharge area for children on home enteral nutrition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventy children were included in the analysis. The mean \u00b1 SD age was 4.7 \u00b1 6 years. The median admission weight\u2010for\u2010age\n                      <jats:italic>Z<\/jats:italic>\n                      \u2010score was \u22121.50. The most common primary diagnosis was a neurological impairment in 37\/70 (47%) children. Most children were fed via a percutaneous endoscopic gastrostomy 31\/70 (44%) and 8\/70 (11%) of the children fed directly into the jejunum. The most common reason being gastrointestinal symptoms, 58\/70 (83%). The most common gastrointestinal symptom reported before commencing an EFI was loose stools in 22\/58 (38%) children. Within 7 days of commencing an EFI, there was reported improvement in gastrointestinal symptoms in all categories. In total, 42\/70 children were discharged on an EFI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In our specialist children's hospital, EFI is primarily implemented by dietitians in children who are already established on an enteral formula displaying gastrointestinal symptoms. However, dietitians are increasingly implementing an EFI as their first\u2010line whole protein enteral formula. Furthermore, an EFI was also implemented as a compromise to a blended diet.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.13374","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T03:04:32Z","timestamp":1729047872000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The impact of an enteral formula with food\u2010derived ingredients on dietetic practice at a specialist children's hospital in the UK: Retrospective study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8625-9264","authenticated-orcid":false,"given":"Graeme","family":"O'Connor","sequence":"first","affiliation":[{"name":"Department of Dietetics Great Ormond Street Hospital Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Camacho","family":"Velandia","sequence":"additional","affiliation":[{"name":"Department of Dietetics Great Ormond Street Hospital Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoltan Hartfiel","family":"Capriles","sequence":"additional","affiliation":[{"name":"Department of Biometry Statistics Sofpromed Clinical Investigation Palma de Mallorca Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533614561791"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/cch.13222"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1510"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533616662993"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533616669703"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1049"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.11055"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000003601"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13090"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13143"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10960"},{"issue":"4","key":"e_1_2_10_13_1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1002\/ncp.10812","article-title":"Monitor gastrointestinal tolerance in children who have switched to an \u201centeral formula with food\u2010derived ingredients\u201d: A national, multicenter retrospective chart review (RICIMIX study)","volume":"37","author":"O'Connor G","year":"2022","journal-title":"Nutr clin pract: off publ Am Soc Parenter Enter Nutr"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1590\/1984-0462\/2022\/40\/2020419"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.5056\/jnm18035"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.7469.1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002153"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001889"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/03014460.2012.694475"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.tb02378.x"},{"key":"e_1_2_10_21_1","unstructured":"Scientific Advisory Committee on Nutrition (SACN). Dietary reference values for energy.2012. Available from:https:\/\/www.gov.uk\/government\/publications\/sacn-dietary-reference-values-for-energy"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2021-322102"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10975"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13277"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/0884533611416126"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2020.12.012"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.2435"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R036012"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutos.2023.12.002"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11122968"},{"key":"e_1_2_10_31_1","first-page":"A30","article-title":"A single centre retrospective study evaluating the discharge process of newly placed feeding tubes from a specialist children's hospital","volume":"108","author":"Rothman B","year":"2023","journal-title":"Archives of Disease in Childhood"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2019-317090"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12913"}],"container-title":["Journal of Human Nutrition and Dietetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jhn.13374","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T13:20:52Z","timestamp":1743772852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jhn.13374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,16]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jhn.13374"],"URL":"https:\/\/doi.org\/10.1111\/jhn.13374","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JHN.13374\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13374\/v2\/decision1","asserted-by":"object"}]},"ISSN":["0952-3871","1365-277X"],"issn-type":[{"value":"0952-3871","type":"print"},{"value":"1365-277X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,16]]},"assertion":[{"value":"2024-03-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13374"}}