{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:51:30Z","timestamp":1772160690150,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to determine the feasibility of increasing soluble fibre intake via dietary counselling to improve gastrointestinal toxicity and quality of life in patients with gynaecological cancers undergoing pelvic radiotherapy without adverse consequences on radiation treatment (RT) delivery accuracy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A single\u2010arm, single\u2010centre intervention feasibility trial included patients with gynaecological cancers undergoing pelvic RT\u2009\u00b1\u2009chemotherapy at a tertiary hospital. Participants were provided weekly dietary counselling over the duration of their RT (5\u20136 weeks) to increase soluble fibre intake incrementally each week. Stakeholder surveys were also completed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In total, 9 of 14 eligible patients participated (55 years old [SD 13.2], diagnosis: cervical [\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093], endometrial\/uterine [\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20095] and vaginal [\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091]), with the majority categorised as low fibre consumers at baseline (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20096). On average, soluble fibre intake increased by 150% throughout treatment. There were no adverse events or major adjustments required for RT delivery. There were improving trends in the functional subset identified. Results may be confounded by the sample size resulting from limited eligibility (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200914) and a high attrition rate (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Most participants successfully increased their soluble fibre intake throughout treatment, without significant adverse events noted for RT delivery accuracy. These results provide preliminary data to calculate the sample size required to produce meaningful effect sizes. However, this study highlighted challenges in participant recruitment and retention, with limited organisational support and perceived compatibility.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.13402","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T01:59:57Z","timestamp":1732586397000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dietary counselling to increase soluble fibre in patients with gynaecological cancers undergoing pelvic radiotherapy: A feasibility study"],"prefix":"10.1111","volume":"38","author":[{"given":"Emilie","family":"Croisier","sequence":"first","affiliation":[{"name":"School of Human Movement &amp; Nutrition Sciences University of Queensland Brisbane Queensland Australia"},{"name":"Dietetics &amp; Food Services Royal Brisbane and Women's Hospital Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Brown","sequence":"additional","affiliation":[{"name":"Dietetics &amp; Food Services Royal Brisbane and Women's Hospital Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Grigg","sequence":"additional","affiliation":[{"name":"Radiation Therapy Royal Brisbane and Women's Hospital Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Chan","sequence":"additional","affiliation":[{"name":"Radiation Oncology Royal Brisbane and Women's Hospital Brisbane Queensland Australia"},{"name":"School of Medicine University of Queensland Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judy","family":"Bauer","sequence":"additional","affiliation":[{"name":"Nutrition, Dietetics and Food Monash University Notting Hill Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(07)70341-8"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.77.4273"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctro.2023.100671"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.02530"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.02831"},{"issue":"1","key":"e_1_2_10_7_1","article-title":"Interventions to reduce acute and late adverse gastrointestinal effects of pelvic radiotherapy for primary pelvic cancers","volume":"1","author":"Lawrie TA","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0029665118000101"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2020.08.077"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jand.2016.09.021"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R036012"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu8090558"},{"key":"e_1_2_10_13_1","volume-title":"Nutrient reference values for Australia and New Zealand","author":"Intakes IR","year":"2005"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfca.2018.05.004"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCO.0000000000000389"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13746"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40814-020-00634-w"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.10.007"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju244"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1280836"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874-018-0591-x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.02.059"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLR.0b013e3182408812"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10488-010-0319-7"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.23.5.443"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/1747-0080.12712"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12919"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14173534"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/dme.14228"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ncp.10677"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2022.2131410"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz7015"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13209"}],"container-title":["Journal of Human Nutrition and Dietetics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jhn.13402","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T13:36:37Z","timestamp":1743773797000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jhn.13402"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1111\/jhn.13402"],"URL":"https:\/\/doi.org\/10.1111\/jhn.13402","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JHN.13402\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13402\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13402\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13402\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JHN.13402\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0952-3871","1365-277X"],"issn-type":[{"value":"0952-3871","type":"print"},{"value":"1365-277X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,25]]},"assertion":[{"value":"2024-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13402"}}