{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T11:20:00Z","timestamp":1782300000134,"version":"3.54.5"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Increasing numbers of elderly co\u2010morbid patients with end\u2010stage kidney disease (ESKD) are now offered haemodialysis. Simple, rapid screening tools are required to risk\u2010assess patients, highlighting those requiring nutritional or other support and advising on prognosis. As such, we assessed a newly introduced tool, the hand grip strength index (HGS index), a comparison of measured to predicted HGS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed ESKD dialysis patients dialysing under the care of an inner\u2010city tertiary dialysis centre who had contemporaneous HGS measurements, and body composition measured by multifrequency bioelectrical impedance analysis, followed for \u2264\u20099 years, censoring for transplantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Results from 1023 patients, 63.2% male, 48.2% White and 46.5% diabetic, with a dialysis vintage of 21.2 (7.2\u201361.0) months, were analysed. Mortality was significantly greater for those in the lowest HGS index quartile using Kaplan\u2013Meier analysis (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). On multivariable step\u2010backward Cox regression analysis, mortality was independently significantly associated (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) with increasing age (hazard ratio [HR] 1.04 95% confidence interval (CI) [1.029\u20131.045]), higher co\u2010morbidity score (HR 1.24 [1.142\u20131.347]) and post\u2010dialysis extracellular water\/total body water ratio (HR 1.15 [1.089\u20131.219]) and lower HGS index (HR \u22120.76 [0.991\u20130.998]), whereas sarcopenia and frailty were not retained in the model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Increasing numbers of elderly co\u2010morbid patients are being treated with dialysis, so simple screening tools are required to advise on prognosis and highlight patients who may need additional support, including nutrition. We found the HGS index to have prognostic value, along with the traditional risk factors of patient age and co\u2010morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.13414","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T04:48:49Z","timestamp":1734410929000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hand Grip Strength Index, a Novel Tool in Risk\u2010Assessing Multi\u2010Ethnic End\u2010Stage Kidney Disease Patients Treated by Haemodialysis"],"prefix":"10.1111","volume":"38","author":[{"given":"Mai","family":"Nguyen","sequence":"first","affiliation":[{"name":"UCL Centre for Kidney &amp; Bladder Health, Royal Free Hospital, University College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4467-6833","authenticated-orcid":false,"given":"Andrew","family":"Davenport","sequence":"additional","affiliation":[{"name":"UCL Centre for Kidney &amp; Bladder Health, Royal Free Hospital, University College London London 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