{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T05:16:47Z","timestamp":1773551807197,"version":"3.50.1"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T00:00:00Z","timestamp":1745712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Coeliac disease is an autoimmune disorder resulting from the consumption of gluten in genetically susceptible individuals. Current treatment is a lifelong gluten\u2010free diet that significantly affects quality of life. Food\u2010related quality of life (FRQoL) refers to the impact of food, nutrition, eating and drinking on the psychosocial aspects of life. The aim of this study was to examine FRQoL in patients with coeliac disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with confirmed coeliac disease completed the validated FR\u2010QoL\u201029 questionnaire adapted for coeliac disease (FR\u2010QoL\u201029\u2010Coeliac) and provided demographic and clinical information.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Questionnaires were completed by 138 adults (62% female, mean age 52.3\u2009SD\u2009\u00b1\u200918.6). FR\u2010QoL\u201029 scores were mean 85.8 (SD\u2009\u00b1\u200923.1). The lowest FR\u2010QoL\u201029 scores were in the 18\u201335 year age group (76.6\u2009\u00b1\u200917.2) compared with the highest in the 56+ age group (92.5\u2009\u00b1\u200922.3,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Patients with \u2265\u20094 gastrointestinal (GiS) symptoms had significantly lower FR\u2010QoL\u201029 scores (77.9\u2009\u00b1\u200920.7) compared with those with 1\u20133 GiS (96.7\u2009\u00b1\u200921,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>FRQoL is impaired in coeliac disease and is particularly lower in younger people and those with greater GI symptom burden. Further research should examine the mechanisms that reduce FRQoL in coeliac disease to identify interventions that minimise the burden for patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.70051","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T01:04:52Z","timestamp":1745802292000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Food Related Quality of Life and Associations With Demographic and Clinical Characteristics in People With Coeliac Disease"],"prefix":"10.1111","volume":"38","author":[{"given":"Nick","family":"Trott","sequence":"first","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Holland","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Hoffmann","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2713-8355","authenticated-orcid":false,"given":"Mohamed G.","family":"Shiha","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suneil A.","family":"Raju","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo A.","family":"Penny","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5414-2950","authenticated-orcid":false,"given":"Kevin","family":"Whelan","sequence":"additional","affiliation":[{"name":"Department of Nutritional Sciences King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.","family":"Sanders","sequence":"additional","affiliation":[{"name":"Academic Unit of Gastroenterology Sheffield Teaching Hospitals Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,4,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000523"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640619844125"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.04.021"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13137"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2014.29"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.0284-2020"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-016-4175-5"},{"key":"e_1_2_9_9_1","unstructured":"Coeliac U.K. \u201cThe Guten Free Diet: How Much Does it Cost and Why Does it Matter? \u201d 2023."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12754"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14791"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-277X.2011.01160.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.13231"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2009.04053.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2021.111249"},{"issue":"13","key":"e_1_2_9_16_1","first-page":"1","article-title":"An Interpretative Phenomenological Analysis of the Development and Maintenance of Gluten\u2010Related Distress and Unhelpful Eating and Lifestyle Patterns in Coeliac Disease","volume":"27","author":"Satherley R. 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