{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:04:05Z","timestamp":1773335045970,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Obesity increases the risk of complications in colorectal cancer surgery. While preoperative very low calorie diet (VLCD) interventions may provide weight loss prior to various surgeries, no data on preoperative VLCD in colorectal cancer surgery exist. This retrospective cohort study therefore aimed to evaluate the efficacy and safety of a dietitian\u2010led preoperative VLCD clinic for adults with obesity prior to colorectal cancer surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients who received the VLCD clinic intervention between 2017 and 2023 were matched 1:1 with adults who did not receive VLCD clinic intervention (controls). Primary outcome was efficacy, measured as \u2265\u20093% weight change from baseline to surgery. Secondary outcome was safety, measured via occurrence of adverse and serious adverse events during VLCD clinic intervention. Descriptive and clinical data were collected from medical charts. Chi\u2010squared, Fisher's exact and nonparametric tests were used to compare data between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thirteen VLCD and 13 controls were recruited (age (median(IQR) 63(59\u201369)years, 65% male). Baseline descriptors were similar, including planned surgical procedure, age and co\u2010morbidities (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). However, VLCD participants were ~9\u2009kg heavier (median(IQR) 114.1(104.5\u2013131.7)kg) at baseline than controls (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The VLCD group lost median 4.75\u2009kg (3.8%) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), with 67% achieving \u2265\u20093% body weight loss from baseline to surgery (median(IQR) 30(18\u201347) days). No VLCD\u2010related adverse events occurred. The VLCD and control groups experienced eight and 15 surgical complications, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A dietitian\u2010led preoperative VLCD clinic intervention achieved weight loss and appears safe. This novel approach may be useful for the preoperative optimisation of colorectal cancer patients with obesity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.70178","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T04:00:16Z","timestamp":1765512016000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Efficacy and Safety of a Preoperative Dietitian\u2010Led Very Low Calorie Diet Clinic for Adults With Obesity for Colorectal Cancer Surgery: A Retrospective Cohort Study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-3026-6344","authenticated-orcid":false,"given":"Rainbow","family":"Lai","sequence":"first","affiliation":[{"name":"Department of Nutrition &amp; Dietetics Logan Hospital  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Palmer","sequence":"additional","affiliation":[{"name":"Department of Nutrition &amp; Dietetics Logan Hospital  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Bloomfield","sequence":"additional","affiliation":[{"name":"Surgical and Critical Care Services Logan Hospital  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasant","family":"Rajan","sequence":"additional","affiliation":[{"name":"Surgical and Critical Care Services Logan Hospital  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynda","family":"Ross","sequence":"additional","affiliation":[{"name":"School of Exercise and Nutrition Sciences Queensland University of Technology  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3006-5601","authenticated-orcid":false,"given":"Sally","family":"Griffin","sequence":"additional","affiliation":[{"name":"Department of Nutrition &amp; Dietetics Logan Hospital  Queensland Australia"},{"name":"Centre for Functioning and Health Research, Metro South Health  Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Health Organization \u201cObesity and Overweight \u201d updated April 2024; 2025 https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/obesity-and-overweight."},{"key":"e_1_2_9_3_1","unstructured":"Australian Government\u2014Australian Institute of Health and Welfare \u201cOverweight and Obesity \u201d updated April 2024; 2025 https:\/\/www.aihw.gov.au\/reports\/overweight-obesity\/overweight-and-obesity\/contents\/summary."},{"key":"e_1_2_9_4_1","unstructured":"Australian Government\u2014Australian Institute of Health and Welfare \u201cCancer Data in Australia \u201d updated April 2024; 2025 https:\/\/www.aihw.gov.au\/reports\/cancer\/cancer-data-in-australia\/contents\/cancer-data-commentaries\/an-overview-of-colorectal-cancer-in-australia."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-016-5209-y"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-015-2174-1"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.13132"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.146"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-021-06394-9"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.116.014258"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13113775"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2022.09.006"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-019-02074-y"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2024.108743"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2005.09.007"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jhn.12819"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61602-X"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2023.09.047"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8223(03)00971-4"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198204223061606"},{"key":"e_1_2_9_21_1","unstructured":"Nestle Health Science \u201cOptifast Very Low Calorie Diet Clinical Treatment Protocol (Version 2) \u201d 2020."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.07.015"},{"issue":"2","key":"e_1_2_9_23_1","first-page":"149","article-title":"Managing Constipation in Adults With Cancer","volume":"8","author":"Wickham R. 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