{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:49:45Z","timestamp":1792043385919,"version":"4.4.0"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100006041","name":"Innovate UK","doi-asserted-by":"publisher","award":["10"],"award-info":[{"award-number":["10"]}],"id":[{"id":"10.13039\/501100006041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006041","name":"Innovate UK","doi-asserted-by":"publisher","award":["047"],"award-info":[{"award-number":["047"]}],"id":[{"id":"10.13039\/501100006041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006041","name":"Innovate UK","doi-asserted-by":"publisher","award":["799"],"award-info":[{"award-number":["799"]}],"id":[{"id":"10.13039\/501100006041","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Human Nutrition Diet"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Malnutrition is highly prevalent among cancer patients receiving systemic anti\u2010cancer therapy (SACT) and is associated with poor treatment tolerance, reduced quality of life, and increased mortality. Despite recommendations, nutritional screening in the outpatient setting is inconsistently implemented and the prognostic significance of nutritional risk identified using a validated screening tool is still unclear. This study aimed to determine the prevalence of nutritional risk among patients receiving SACT, whether their nutritional needs were being met with dietetic input, and to examine associations with clinical outcomes, including treatment toxicity, dose reduction, hospital admission, and overall survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, adult outpatients receiving SACT were invited to complete the Patient\u2010Generated Subjective Global Assessment Short Form (PG\u2010SGA SF), a nutritional screening tool. Nutritional risk using PG\u2010SGA SF scores was assessed in relation to treatment toxicity, dose reduction, and hospital admission using multivariable regression models and survival was evaluated using Cox proportional hazards models, both adjusted for age, sex, metastatic disease, and performance status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 169 participants, 24.9% were at nutritional risk, PG\u2010SGA SF score 4\u20138, and 10.7% at high risk \u2265\u20099, yet only 5.3% were in receipt of dietetic care. Higher PG\u2010SGA SF scores were independently associated with increased treatment toxicity (OR: 1.2, 95% CI: 1.1\u20131.3,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.003) and SACT dose reductions (OR: 1.2, 95% CI: 1.0\u20131.3,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.040). Nutritional risk was not significantly associated with 30\u2010day hospital admissions but was independently associated with overall survival (HR: 1.1, 95% CI: 1.0\u20131.2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nutritional risk identified using the PG\u2010SGA SF independently predicted treatment toxicity, dose reduction, and survival in those receiving SACT. Despite over one\u2010third of those meeting the criteria for dietetic intervention, only 5.3% were receiving dietetic care, indicating a substantial gap between dietetic need and provision. These results support implementation of routine screening, referral pathways, and a dedicated dietetic service integrated into oncology outpatient services.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jhn.70359","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:40:32Z","timestamp":1792042832000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nutritional Risk and Unmet Nutritional Need in Ambulatory Patients Undergoing Systemic Anti\u2010Cancer Therapies"],"prefix":"10.1111","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1486-3383","authenticated-orcid":false,"given":"Amy","family":"McLuskie","sequence":"first","affiliation":[{"name":"Institute of Genetics and Cancer University of Edinburgh Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Angel","sequence":"additional","affiliation":[{"name":"Western General Hospital Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0189-0952","authenticated-orcid":false,"given":"Matthew","family":"Maddocks","sequence":"additional","affiliation":[{"name":"Cicely Saunders Institute of Palliative Care Policy and Rehabilitation, King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3056-059X","authenticated-orcid":false,"given":"Anne","family":"Finucane","sequence":"additional","affiliation":[{"name":"Clinical Psychology, Health in Social Science University of Edinburgh Edinburgh UK"},{"name":"Marie Curie Hospice Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Fallon","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Cancer University of Edinburgh Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2807-6192","authenticated-orcid":false,"given":"Barry J. A.","family":"Laird","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine, Medical Faculty University of Oslo Oslo Norway"},{"name":"Department of Oncology, European Palliative Care Research Centre (PRC) Radium Hospital, Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9197-776X","authenticated-orcid":false,"given":"Michael S.","family":"Yule","sequence":"additional","affiliation":[{"name":"Institute of Genetics and Cancer University of Edinburgh Edinburgh UK"},{"name":"St Columba's Hospice Care Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,14]]},"reference":[{"issue":"8","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/jpen.2688","article-title":"Malnutrition Risk Screening in Adult Oncology Outpatients: An ASPEN Systematic Review and Clinical Recommendations","volume":"48","author":"Trujillo E. 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