{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T05:13:02Z","timestamp":1779167582043,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T00:00:00Z","timestamp":1361923200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest & Clin Dent"],"published-print":{"date-parts":[[2014,8]]},"abstract":"Abstract<\/jats:title>Aim<\/jats:title>The objective of the present study was to detect the presence of P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic> (fimA), A<\/jats:styled-content>ggregatibacter actinomycetemcomitans<\/jats:italic>, and red complex in the coronary plaque of patients with coronary artery disease.<\/jats:p><\/jats:sec>Methods<\/jats:title>The study population consisted of 51 patients with chronic periodontitis undergoing coronary artery bypass grafting. DNA<\/jats:styled-content> was extracted from subgingival and coronary atherosclerotic plaque samples. Polymerase chain reaction was used to amplify the part of 16S rRNA<\/jats:styled-content> gene to detect the presence of A<\/jats:styled-content>ggregatibacter actinomycetemcomitans<\/jats:italic>, P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic> (fimA), P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic>, T<\/jats:styled-content>annerella forsythia<\/jats:italic>, and T<\/jats:styled-content>reponema denticola<\/jats:italic>.<\/jats:p><\/jats:sec>Results<\/jats:title>A<\/jats:styled-content>ggregatibacter actinomycetemcomitans<\/jats:italic>, T<\/jats:styled-content>annerella forsythia<\/jats:italic>, P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic>, P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic> (fimA), and T<\/jats:styled-content>reponema denticola<\/jats:italic> were detected in 0%, 31.4%, 45.1%, 39.2%, and 51% of the atherosclerotic plaque samples, respectively. In both subgingival and coronary atherosclerotic plaque samples, T<\/jats:styled-content>annerella forsythia<\/jats:italic> was detected in 19.6%, P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic> in 39.2%, P<\/jats:styled-content>orphyromonas gingivalis<\/jats:italic> (fimA) in 33.3%, and T<\/jats:styled-content>reponema denticola<\/jats:italic> in 35.3% of the samples.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The study confirmed the detection of red complex bacteria in coronary plaque samples. However A<\/jats:styled-content>ggregatibacter actinomycetemcomitans<\/jats:italic> could not be detected in these samples.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jicd.12030","type":"journal-article","created":{"date-parts":[[2013,2,28]],"date-time":"2013-02-28T19:10:56Z","timestamp":1362078656000},"page":"201-207","source":"Crossref","is-referenced-by-count":9,"title":["Genetic analysis of P<\/scp>orphyromonas gingivalis<\/i> (fimA), A<\/scp>ggregatibacter actinomycetemcomitans,<\/i> and red complex in coronary plaque"],"prefix":"10.1111","volume":"5","author":[{"given":"Jaideep","family":"Mahendra","sequence":"first","affiliation":[{"name":"Department of Periodontology Meenakshi Ammal Dental College Meenakshi Academy of Higher Education and Research Chennai India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Little","family":"Mahendra","sequence":"additional","affiliation":[{"name":"Department of Periodontics Annamalai University Chidambaram India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Felix","sequence":"additional","affiliation":[{"name":"Department of Community Medicine Raja Muthaiah Medical College and Hospital Annamalai University Chidambaram India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios E.","family":"Romanos","sequence":"additional","affiliation":[{"name":"School of Dental Medicine Stony Brook University Stony Brook NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,2,27]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01430.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.5.731"},{"key":"e_1_2_6_4_1","first-page":"313","article-title":"Effects of P.\u00a0gingivalis infection on atheroma formation in ApoE (+\/\u2010) mice","volume":"79","author":"Chung HJ","year":"2000","journal-title":"J Dent Res"},{"key":"e_1_2_6_5_1","first-page":"150","article-title":"Peripheral blood and C\u2010reactive protein levels (CRP) in chronic periodontitis","volume":"3","author":"Rai B","year":"2009","journal-title":"Afr. 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