{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:21:15Z","timestamp":1777364475844,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T00:00:00Z","timestamp":1400716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Many individuals have various tobacco\u2010related habits, yet only some develop clinical manifestation of lesions. This raises the question of whether there any inherent or host risk factors involved in the pathogenesis which need to be further investigated. The aim of the present study was to analyze the <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content> antigen, secretor status, and blood groups of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study consisted of 99 participants, with 33 patients allocated to three groups: (a) patients with a tobacco\u2010related habit and oral submucous fibrosis (<jats:styled-content style=\"fixed-case\">OSF<\/jats:styled-content>); (b) patients with a tobacco\u2010related habit, but no lesions; and (c) healthy controls. A total of 1\u00a0mL unstimulated saliva was collected in a sterile test tube, and the <jats:styled-content style=\"fixed-case\">W<\/jats:styled-content>iener agglutination test was performed to analyze the <jats:styled-content style=\"fixed-case\">ABO<\/jats:styled-content> antigen in all three groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All of the <jats:styled-content style=\"fixed-case\">OSF<\/jats:styled-content> patients were non\u2010secretors, whereas 84.8% were non\u2010secretors in the group of individuals with habits as compared to 15.2% in the healthy group. A statistically\u2010significant difference was observed between the <jats:styled-content style=\"fixed-case\">OSF<\/jats:styled-content> and healthy groups. The patients in the <jats:styled-content style=\"fixed-case\">OSF<\/jats:styled-content> group were predominantly blood\u2010group A, followed by groups O, B, and <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There is a correlation between salivary secretor status and the development of <jats:styled-content style=\"fixed-case\">OSF<\/jats:styled-content>. Thus, non\u2010secretors are at greater risk of and more prone to the development of oral lesions. Blood\u2010groups A and O predominate over the B and <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> blood groups.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jicd.12100","type":"journal-article","created":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T08:38:04Z","timestamp":1400747884000},"page":"261-266","source":"Crossref","is-referenced-by-count":4,"title":["Analysis of salivary secretor status in patients with oral submucous fibrosis: a case\u2010control study"],"prefix":"10.1111","volume":"6","author":[{"given":"Kaveri","family":"Hallikeri","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Sri Dharamasthala Manjunatheshwara College of Dental Sciences &amp; Hospital Dharwad Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravichandra","family":"Udupa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology Sri Dharamasthala Manjunatheshwara College of 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