{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T11:06:29Z","timestamp":1770980789997,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T00:00:00Z","timestamp":1405555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of the present investigation was to evaluate and compare the efficacy of resorbable collagen\u2010based tetracycline fibers (Periodontal Plus <jats:styled-content style=\"fixed-case\">AB<\/jats:styled-content> fibers) given as an adjunct to scaling and root planing, with the clinical effects of scaling and root planning delivered as a monotherapy, in the treatment of chronic periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A split\u2010mouth design was used to conduct this study. Forty patients with periodontal pockets ranging from \u22655\u00a0mm to \u22647\u00a0mm, with minimum of two sites in two non\u2010adjacent quadrants, were selected for the study. The treatment sites in each patient were randomly divided into the control and experimental groups. All of the selected sites were treated with scaling and root planning, and then collagen\u2010based resorbable tetracycline fibers were placed adjunctively in the experimental sites at the same visit. Baseline and follow\u2010up measurements in both treatment groups included plaque index, sulcus bleeding index, probing pocket depth, and relative attachment level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Although significant clinical benefits were obtained in both treatment groups, the adjunctive antimicrobial use of tetracycline fibers demonstrated better results compared to the control group over the 3\u2010month observational period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The delivery of antimicrobial agent tetracycline in a collagen matrix was found to improve the benefits of scaling and root planing by a larger magnitude in patients with moderate\u2010to\u2010deep pockets.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jicd.12111","type":"journal-article","created":{"date-parts":[[2014,7,17]],"date-time":"2014-07-17T11:52:18Z","timestamp":1405597938000},"page":"307-312","source":"Crossref","is-referenced-by-count":12,"title":["Clinical utility of locally\u2010delivered collagen\u2010based biodegradable tetracycline fibers in periodontal therapy: an <i>in vivo<\/i> study"],"prefix":"10.1111","volume":"6","author":[{"given":"Fayiza Yaqoob","family":"Khan","sequence":"first","affiliation":[{"name":"Post\u2010Graduate Departments of Periodontics and Conservative Dentistry Government Dental College and Hospital Srinagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhail Majid","family":"Jan","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Departments of Periodontics and Conservative Dentistry Government Dental College and Hospital Srinagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mubashir","family":"Mushtaq","sequence":"additional","affiliation":[{"name":"Post\u2010Graduate Departments of Periodontics and Conservative Dentistry Government Dental College and Hospital Srinagar India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,7,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345700490020401"},{"key":"e_1_2_6_3_1","first-page":"12","article-title":"Microbial etiology of periodontal diseases. Where are we? Where are we going?","volume":"2","author":"Tanner A","year":"1992","journal-title":"Curr Opin Dent"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb00460.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1991.0277"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.8s.782"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1981.52.10.613"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.8.692"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1995.268.5.C1090"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02039.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb00765.x"},{"issue":"25","key":"e_1_2_6_12_1","first-page":"77","article-title":"Nonsurgical periodontal therapy","volume":"2001","author":"Drisko CH","year":"2000","journal-title":"Periodontol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1980.tb01963.x"},{"key":"e_1_2_6_14_1","first-page":"58","article-title":"Professional mechanical oral hygiene practices in the prevention and control of periodontal diseases","volume":"13","author":"Walsh MM","year":"1975","journal-title":"Calif Dent Assoc J"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.10.552"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb1978.14.72"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1979.tb01935.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.2.118"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0087"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0303-6979.2004.00457.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02514.x"},{"key":"e_1_2_6_22_1","first-page":"6","article-title":"Clinical significance of non\u2010surgical periodontal therapy: an evidence based perspective of scaling and root planing","volume":"29","author":"Cobb CM","year":"2002","journal-title":"J Periodontol"},{"key":"e_1_2_6_23_1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1600-051X.1990.tb01070.x","article-title":"Scores of plaque, bleeding, suppuration, and probing depth to predict probing attachment loss: 5\u00a0years of observation following non\u2010surgical periodontal therapy","volume":"17","author":"Baderstein A","year":"1990","journal-title":"J Clin Periodontol"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1980.tb02154.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1991.tb02076.x"},{"key":"e_1_2_6_26_1","first-page":"421","article-title":"Principle and clinical applications of periodontal controlled drug delivery with tetracycline fibers","volume":"14","author":"Tonetti MS","year":"1994","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_27_1","first-page":"151","article-title":"Gingival response to subgingival placement of monolithic tetracycline\u2010 impregnated fibers: microscopic observations","volume":"13","author":"Kazakos GM","year":"1993","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_6_28_1","first-page":"450","volume-title":"Textbook of periodontology","author":"Nyman S","year":"1983"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb01699.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1986.tb01466.x"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1987.tb01580.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1990.tb00923.x"}],"container-title":["Journal of Investigative and Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjicd.12111","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjicd.12111","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jicd.12111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T18:25:05Z","timestamp":1696184705000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jicd.12111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,17]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["10.1111\/jicd.12111"],"URL":"https:\/\/doi.org\/10.1111\/jicd.12111","archive":["Portico"],"relation":{},"ISSN":["2041-1618","2041-1626"],"issn-type":[{"value":"2041-1618","type":"print"},{"value":"2041-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,17]]}}}