{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T23:21:34Z","timestamp":1773703294358,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the present study was to analyze caries experience in relation to the occurrence of fluorosis in 12\u00a0year olds in a natural fluoride area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study was conducted among 12\u2010year\u2010old lifetime residents (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>301) of Klaipeda, Lithuania, where the natural fluoride content is 1.7\u20132.2\u00a0ppm F. Data collection included a clinical dental examination and an inquiry about toothbrushing habits. Dental caries was diagnosed according to the World Health Organization criteria and described in terms of decayed, missing, and filled teeth (<jats:styled-content style=\"fixed-case\">DMFT<\/jats:styled-content>)\/decayed, missing and filled surfaces (<jats:styled-content style=\"fixed-case\">DMFS<\/jats:styled-content>) indices and decayed, filled surfaces (DFS) on selected proximal surfaces. Dental fluorosis was diagnosed according to the Thylstrup\u2013Fejerskov (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>) index and categorized as none (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0=\u00a00), mild (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0=\u00a01\u20132), moderate (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0=\u00a03\u20137), or severe (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0=\u00a08\u20139). The <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2010, Kruskal\u2013Wallis, and Mann\u2013Whitney tests, Pearson's correlation, and linear regression served for statistical analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 34% of the 12\u00a0year olds studied had no signs of fluorosis, while the rest had mild (42%) or moderate (24%) fluorosis. Caries experience was negatively related to the presence of fluorosis. When present (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0&gt;\u00a00), the\u00a0mean <jats:styled-content style=\"fixed-case\">DMFT<\/jats:styled-content> was 1.8 (standard deviation [<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>]: 1.7) versus 2.6 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>: 2.3) in the absence of fluorosis (<jats:styled-content style=\"fixed-case\">TF<\/jats:styled-content>\u00a0=\u00a00, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.008). The corresponding mean <jats:styled-content style=\"fixed-case\">DMFS<\/jats:styled-content> values were 2.6 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>: 3.1) versus 3.8 (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>: 4.3, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.014).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presence of fluorosis associates with lesser caries experience in 12\u2010year\u2010old lifetime residents of an area with moderately\u2010elevated natural fluoride.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jicd.12137","type":"journal-article","created":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T06:59:23Z","timestamp":1417417163000},"page":"187-192","source":"Crossref","is-referenced-by-count":3,"title":["Variation in fluorosis and caries experience among Lithuanian 12\u00a0year olds exposed to more than 1\u00a0ppm F in tap water"],"prefix":"10.1111","volume":"7","author":[{"given":"Julija","family":"Narbutait\u0117","sequence":"first","affiliation":[{"name":"Clinic for Preventive and Paediatric Dentistry Faculty of Odontology Lithuanian University of Health Sciences Kaunas Lithuania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorma I.","family":"Virtanen","sequence":"additional","affiliation":[{"name":"Department of Community Dentistry Institute of Dentistry University of Oulu Oulu Finland"},{"name":"Oulu University Hospital Oulu Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miira M.","family":"Vehkalahti","sequence":"additional","affiliation":[{"name":"Department of Community Dentistry Institute of Dentistry University of Oulu Oulu Finland"},{"name":"Oulu University Hospital Oulu Finland"},{"name":"Department of Oral Public Health Institute of Dentistry University of Helsinki Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2307\/4582632"},{"key":"e_1_2_5_3_1","volume-title":"Fluorides and oral health. 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