{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:51:42Z","timestamp":1772160702933,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,6,26]],"date-time":"2016-06-26T00:00:00Z","timestamp":1466899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      There is a lack of appropriate, commercially\u2010available topical corticosteroid formulations for use in oral lichen planus (\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      ) and oral lichenoid reaction. Current therapy includes crushing a dexamethasone tablet and mixing it with water for use as a mouth rinse. This formulation is unpleasant esthetically and to use in the mouth, as it is a bitter and gritty suspension, resulting in poor compliance. Thus, the present study was designed to formulate and pilot an effective, esthetically\u2010pleasing formulation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A single\u2010blinded, cross\u2010over trial was designed with two treatment arms. Patients were monitored for 7 weeks. Quantitative and qualitative data was assessed using\n                      <jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>\n                      , numeric pain scales, the Treatment Satisfaction Questionnaire for Medication\u20109, and thematic analysis to determine primary patient\u2010reported outcomes, including satisfaction, compliance, quality of life, and symptom relief.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Nine patients completed the pilot trial. Data analysis revealed the new compounded formulation to be superior to existing therapy due to its convenience, positive contribution to compliance, patient\u2010perceived faster onset of action, and improved symptom relief.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Topical dexamethasone is useful in the treatment of\n                      <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>\n                      . When carefully formulated into a compounded mouth rinse, it improves patient outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jicd.12225","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T00:12:47Z","timestamp":1466986367000},"source":"Crossref","is-referenced-by-count":12,"title":["Comparison between self\u2010formulation and compounded\u2010formulation dexamethasone mouth rinse for oral lichen planus: a pilot, randomized, cross\u2010over trial"],"prefix":"10.1111","volume":"8","author":[{"given":"Jessica L.","family":"Hambly","sequence":"first","affiliation":[{"name":"School of Pharmacy Menzies Health Institute Queensland Griffith University Gold Coast QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Haywood","sequence":"additional","affiliation":[{"name":"School of Pharmacy Menzies Health Institute Queensland Griffith University Gold Coast QLD Australia"},{"name":"Mater Research Institute The University of Queensland Brisbane QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laetitia","family":"Hattingh","sequence":"additional","affiliation":[{"name":"School of Pharmacy Menzies Health Institute Queensland Griffith University Gold Coast QLD Australia"},{"name":"School of Pharmacy Curtin University Perth WA Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj G.","family":"Nair","sequence":"additional","affiliation":[{"name":"School of Dentistry Oral Health, Oral Medicine and Oral Oncology Menzies Health Institute Queensland Griffith University Gold Coast QLD Australia"},{"name":"Haematology and Oncology Gold Coast University Hospital Gold Coast QLD Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,6,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2008.00662.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2011.10.013"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2010.01196.x"},{"key":"e_1_2_6_5_1","first-page":"1","article-title":"Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations","volume":"103","author":"Al\u2010Hashimi I","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599812473237"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/154411130201300405"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(68)90194-1"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1054\/bjom.2000.0335"},{"key":"e_1_2_6_10_1","first-page":"127","article-title":"Multimodality steroid therapy of erosive and ulcerative oral lichen planus","volume":"38","author":"Zegarelli DJ","year":"1983","journal-title":"J Oral Med"},{"key":"e_1_2_6_11_1","first-page":"1130","article-title":"Potential hazards of topical steroid therapy","volume":"137","author":"Stoppoloni G","year":"1983","journal-title":"Am J Dis Child"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.4.472"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.076"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.09.006"},{"key":"e_1_2_6_15_1","first-page":"1","article-title":"Interventions for treating oral lichen planus","volume":"7","author":"Thongprasom K","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_16_1","unstructured":"Phoenix Medical Publishing Pty Ltd 2006\u20102013. 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