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Blood samples were obtained, and the isolated <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> was used to amplify exons 4\u20108 of the <jats:italic>p53<\/jats:italic> gene using specific primers, and subsequently sequenced. No mutations were identified in the coding regions of the <jats:italic>p53<\/jats:italic> gene. A review of the literature revealed a prevalence of <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content> associated with <jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content> to be as high as 13.6%, and that 83% of the case reports performed enucleation of <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content> and removal of <jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content>. Dentigerous cysts associated with <jats:styled-content style=\"fixed-case\">ST<\/jats:styled-content> in one sibling demonstrated that variations in phenotypes exist, and the absence of mutations cannot eliminate the potential influence of genetic risk factors.<\/jats:p>","DOI":"10.1111\/jicd.12267","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T04:33:19Z","timestamp":1491539599000},"source":"Crossref","is-referenced-by-count":7,"title":["Genetic basis of dentigerous cysts associated with supernumerary teeth: A narrative review"],"prefix":"10.1111","volume":"9","author":[{"given":"Robert P.","family":"Anthonappa","sequence":"first","affiliation":[{"name":"School of Dentistry University of Western Australia  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9156-3727","authenticated-orcid":false,"given":"Manikandan","family":"Ekambaram","sequence":"additional","affiliation":[{"name":"The University of Hong Kong  Hong Kong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaturi N. 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