{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T18:35:02Z","timestamp":1784399702527,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T00:00:00Z","timestamp":1497916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Boric acid (<jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>) exhibits antibacterial, anti\u2010inflammatory, as well as osteoblastic, activity. The aim of the present study was to explore the efficacy of 0.75% <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> gel as a local drug\u2010delivery system in adjunct to scaling and root planing (<jats:styled-content style=\"fixed-case\">SRP<\/jats:styled-content>) for the treatment of class <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> furcation defects in comparison with placebo gel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 48 mandibular class <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> furcation defects were randomized and treated with either 0.75% <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> gel or placebo gel. Clinical parameters were recorded at baseline, 3\u00a0months, and 6\u00a0months, while radiographic parameters were recorded at baseline and 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Greater mean probing depth reduction and mean relative vertical and horizontal clinical attachment level gain were shown to be greater in group 1 than in group 2 at 3 and 6\u00a0months. Furthermore, a significantly greater mean percentage of bone fill was found in group 1 (16.98%\u00b11.03%) than in the placebo (2.86%\u00b10.92%) at 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The .75% <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> group showed significant improvement in clinical parameters compared to placebo gel as an adjunct to <jats:styled-content style=\"fixed-case\">SRP<\/jats:styled-content>. This implies an alternative for treatment of class <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> furcation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jicd.12279","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T11:18:47Z","timestamp":1497957527000},"source":"Crossref","is-referenced-by-count":17,"title":["Boric acid gel as local drug delivery in the treatment of class <scp>II<\/scp> furcation defects in chronic periodontitis: a randomized, controlled clinical trial"],"prefix":"10.1111","volume":"9","author":[{"given":"Sandeep","family":"Singhal","sequence":"first","affiliation":[{"name":"Department of Periodontology Government Dental College and Research Institute  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7217-9519","authenticated-orcid":false,"given":"Avani Raju","family":"Pradeep","sequence":"additional","affiliation":[{"name":"Department of Periodontology Government Dental College and Research Institute  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmendra","family":"Kanoriya","sequence":"additional","affiliation":[{"name":"Department of Periodontology Government Dental College and Research Institute  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Periodontology Government Dental College and Research Institute  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibhuti","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Periodontology Government Dental College and Research Institute  Bangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,6,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1978.49.5.225"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.7.402"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jebdp.2011.12.005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1990.tb01083.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.12.683"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.12.675"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.12.664"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1993.64.11.1052"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.11.1580"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00947.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01428.x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.9.1282"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110716"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2008.00023.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2011.07.012"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910808700208"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2006.08.130"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2014.898789"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.120467"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-011-9094-x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2008.01.011"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1975.tb01727.x"},{"key":"e_1_2_7_24_1","first-page":"107","article-title":"Gingival sulcus bleeding \u2014 A leading symptom in initial gingivitis","volume":"15","author":"Muhlemann HR","year":"1971","journal-title":"Helv Odontol Acta"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","unstructured":"SilnessJ.Lo\u00a8e H. 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