{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T14:25:47Z","timestamp":1774794347741,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T00:00:00Z","timestamp":1546819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Invest & Clin Dent"],"published-print":{"date-parts":[[2019,5]]},"abstract":"Abstract<\/jats:title>The aim of the present study was to comprehensively review the influence of psychological stress exposure (PSE<\/jats:styled-content>) on orthodontic therapy (OT<\/jats:styled-content>). Original clinical and experimental studies were assessed. Quality assessment of experimental studies was performed using the Animal Research Reporting In Vivo Experiment (ARRIVE<\/jats:styled-content>) guidelines. Six studies (2 clinical and 4 experimental) were included. One clinical study showed that PSE<\/jats:styled-content> during OT<\/jats:styled-content> significantly increases nickel release from orthodontic appliances into the saliva. In another study, maternal support was found to be an important predictor of the outcome of OT<\/jats:styled-content>. In one experimental study, chronic PSE<\/jats:styled-content> increased orthodontic tooth movement (OTM<\/jats:styled-content>), and in two experimental studies, PSE<\/jats:styled-content> decreased OTM<\/jats:styled-content>. One study on rats reported that PSE<\/jats:styled-content> is not a risk factor for orthodontically\u2010induced root resorption during OTM<\/jats:styled-content>. One experimental study showed a significantly higher number of osteoclasts in the bone on the side of OTM<\/jats:styled-content> in restrained rats compared with unrestrained rats. One study showed decreased osteoclast counts in the bone during OTM<\/jats:styled-content> under PSE<\/jats:styled-content>. The lowest, highest, and mean ARRIVE<\/jats:styled-content> scores (out of 20) for the experimental studies were 16, 18, and 16.75\u00a0\u00b1\u00a00.96, respectively. The role of PSE<\/jats:styled-content> in clinical orthodontics remains unclear, most likely due to a lack of studies in humans. Further power\u2010adjusted, well\u2010designed, and randomized studies are needed.<\/jats:p>","DOI":"10.1111\/jicd.12388","type":"journal-article","created":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T03:12:17Z","timestamp":1547003537000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Influence of psychological stress exposure on orthodontic therapy: A comprehensive review"],"prefix":"10.1111","volume":"10","author":[{"given":"Deema","family":"Al\u2010Shammery","sequence":"first","affiliation":[{"name":"Department of Orthodontics Riyadh Elm University Riyadh Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-4406","authenticated-orcid":false,"given":"Dimitrios","family":"Michelogiannakis","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics Eastman Institute for Oral Health University of Rochester Rochester New York"},{"name":"Department of Community Dentistry and Oral Disease Prevention Eastman Institute for Oral Health University of Rochester Rochester New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emile","family":"Rossouw","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics Eastman Institute for Oral Health University of Rochester Rochester New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios E.","family":"Romanos","sequence":"additional","affiliation":[{"name":"Department of Periodontology Stony Brook University Stony Brook New York"},{"name":"Department of Oral Surgery and Implant Dentistry University of Frankfurt Frankfurt Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9253-1989","authenticated-orcid":false,"given":"Fawad","family":"Javed","sequence":"additional","affiliation":[{"name":"Department of Periodontology Stony Brook University Stony Brook New York"},{"name":"Department of General Dentistry Eastman Institute for Oral Health University of Rochester Rochester New York"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,1,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2018.20.1\/mdehert"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1995.66.11.990"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055875"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2007.12.004"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(05)81579-3"},{"key":"e_1_2_6_7_1","first-page":"371","article-title":"Effect of stress on postnatal growth in weight of rat body and adrenal gland","volume":"34","author":"Kirillov OI","year":"2003","journal-title":"Ontogenez"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(01)00422-7"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12273"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-013-9812-7"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjr111"},{"key":"e_1_2_6_12_1","first-page":"121","article-title":"The effects of systemic stress on orthodontic tooth movement","volume":"24","author":"Gameiro GH","year":"2008","journal-title":"Aust Orthod J"},{"key":"e_1_2_6_13_1","first-page":"569","article-title":"Evaluation of root resorption associated with orthodontic movement in stressed rats","volume":"57","author":"Gameiro GH","year":"2008","journal-title":"Minerva Stomatol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.16.e285"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjp106"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2945"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1258\/la.2010.0010021"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12406"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2018.05.016"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2018.07.033"},{"key":"e_1_2_6_21_1","first-page":"422","article-title":"Factors affecting patient satisfaction after orthodontic treatment","volume":"76","author":"Al\u2010Omiri MK","year":"2006","journal-title":"Angle Orthod"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/107755879605300101"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2016.05.009"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-011-9006-0"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2002.00845.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.240560304"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0195722"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2013-1139"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.4103\/0976-500X.119726"}],"container-title":["Journal of Investigative and Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjicd.12388","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jicd.12388","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jicd.12388","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jicd.12388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T21:55:08Z","timestamp":1694382908000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jicd.12388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,7]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,5]]}},"alternative-id":["10.1111\/jicd.12388"],"URL":"https:\/\/doi.org\/10.1111\/jicd.12388","archive":["Portico"],"relation":{},"ISSN":["2041-1618","2041-1626"],"issn-type":[{"value":"2041-1618","type":"print"},{"value":"2041-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,7]]},"assertion":[{"value":"2018-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12388"}}