{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T13:38:18Z","timestamp":1786628298390,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T00:00:00Z","timestamp":1565481600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this systematic review was to determine the efficacy of gabapentin (GBP) in the treatment of pain of\u00a0 idiopathic trigeminal neuralgia (TN). A comprehensive literature search was conducted using the Cumulative Index of Nursing and Allied Health Literature (EBSCO Industries), Emcare (Ovid), Medline (Ovid), Medline (PubMed), Scopus (Elsevier) and Web of Science (Clarivate Analytics). The inclusion criteria comprised randomized controlled trials of GBP as a monotherapy in the treatment of idiopathic TN in adult participants and publications in English. All other study methodologies were excluded. The search yielded 1472 articles, and after exclusion, 11 full\u2010text articles were eligible for full\u2010text analysis. Only two studies met the inclusion criteria. There is insufficient evidence either to support or refute the efficacy of GBP in the management of idiopathic TN. Therefore, further well\u2010designed placebo\u2010controlled trials are required to confirm the efficacy of GBP in managing TN pain as a single therapy.<\/jats:p>","DOI":"10.1111\/jicd.12448","type":"journal-article","created":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T06:53:12Z","timestamp":1565592792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Efficacy of gabapentin in the treatment of trigeminal neuralgia: A systematic review of randomized controlled trials"],"prefix":"10.1111","volume":"10","author":[{"given":"Patrick Chieu Poa","family":"Ta","sequence":"first","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hue Quyen","family":"Dinh","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Nguyen","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Li","family":"Ong","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-7045","authenticated-orcid":false,"given":"Anura","family":"Ariyawardana","sequence":"additional","affiliation":[{"name":"College of Medicine and Dentistry James Cook University Cairns QLD Australia"},{"name":"Metro South Oral Health, Queensland Health Brisbane QLD Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,11]]},"reference":[{"key":"e_1_2_5_2_1","unstructured":"International association for the study of pain. 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