{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T20:21:54Z","timestamp":1785529314312,"version":"3.56.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T00:00:00Z","timestamp":1567382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Invest &amp; Clin Dent"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To seek scientific evidence to support the effectiveness of invisible aligners, in the aesthetic and functional aspects, compared with that of conventional braces. An electronic search was performed with a complementary grey literature search for in vivo research. No language restrictions were applied. Scopus, PubMed, Web of Science, Cochrane, ClinicalTrials and GreyLiterature databases were used. Studies were first selected by title and abstract; those potentially eligible were read in full. Non\u2010randomized studies were assessed for risk of bias using the tools Methodological Index for Non\u2010randomized Studies (MINORS) and Cochrane Collaboration Common Scheme for Bias as a function of the presence of randomization. The search found 559 studies, of which 55 were potentially eligible. A total of 4 articles were included in this systematic literature review: three non\u2010randomized controlled studies and one randomized controlled study, three with low risk of bias (RoB) and one with moderate RoB. Three studies showed time of correction of dental crowding shorter or equal to that of the control group and only one study showed less time of correction using conventional braces. Invisible aligners were deficient with respect to anterior\/posterior and vertical corrections compared with fixed orthodontic appliances. Invisible aligners are effective in promoting dental alignment, but present clinical limitations in relation to the conventional system.<\/jats:p>","DOI":"10.1111\/jicd.12455","type":"journal-article","created":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T06:59:21Z","timestamp":1567493961000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Assessment of the effectiveness of invisible aligners compared with conventional appliance in aesthetic and functional orthodontic treatment: A systematic review"],"prefix":"10.1111","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8418-4139","authenticated-orcid":false,"given":"Matheus Melo","family":"Pithon","sequence":"first","affiliation":[{"name":"Departament of Health I Southwest Bahia State University UESB Jequi\u00e9 Bahia Brazil"},{"name":"Department of Pediatric Dentistry and Orthodontics, School of Dentistry Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Carvalho Souza","family":"Bai\u00e3o","sequence":"additional","affiliation":[{"name":"Departament of Health I Southwest Bahia State University UESB Jequi\u00e9 Bahia Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia Iandeyara Dantas de Andrade","family":"Sant\u00b4 Anna","sequence":"additional","affiliation":[{"name":"Departament of Health I Southwest Bahia State University UESB Jequi\u00e9 Bahia Brazil"},{"name":"Department of Pediatric Dentistry and Orthodontics, School of Dentistry Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Renato","family":"Paranhos","sequence":"additional","affiliation":[{"name":"Department of Social and Preventive Dentistry, School of Dentistry, Federal University of Uberl\u00e2ndia Universidade Federal de Uberl\u00e2ndia Uberl\u00e2ndia Minas Gerais Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucianne","family":"Cople Maia","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry and Orthodontics, School of Dentistry Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,2]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.0022-0337.2008.72.8.tb04570.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjr086"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0096-6347(45)90101-3"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2005.06.002"},{"key":"e_1_2_5_6_1","volume-title":"Orthodontics and dentofacial orthopedics","author":"McNamara JA","year":"2001"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2006.05.031"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00056-010-1040-6"},{"issue":"3","key":"e_1_2_5_9_1","first-page":"263","article-title":"Clinical limitations of Invisalign","volume":"73","author":"Phan X","year":"2007","journal-title":"J Can Dent Assoc"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x"},{"key":"e_1_2_5_11_1","unstructured":"HigginsJPT GreenS.Cochrane Handbook for systematic reviews of interventions. Version 5.1.0 [updated March 2011]2011 August 2016. Available fromhttp:\/\/handbook.cochrane.org\/"},{"issue":"1","key":"e_1_2_5_12_1","first-page":"23","article-title":"Self\u2010ligating versus Invisalign: analysis of dento\u2010alveolar effects","volume":"2","author":"Pavoni C","year":"2011","journal-title":"Ann Stomatol (Roma)"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2319\/100106-398.1"},{"issue":"5","key":"e_1_2_5_14_1","first-page":"8276","article-title":"The effectiveness of the Invisalign appliance in extraction cases using the the ABO model grading system: a multicenter randomized controlled trial","volume":"8","author":"Li W","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsi.2014.10.016"},{"issue":"10","key":"e_1_2_5_16_1","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1080\/19424396.2002.12223318","article-title":"Clinical evolution of the Invisalign appliance","volume":"30","author":"Vlaskalic V","year":"2002","journal-title":"J Calif Dent Assoc"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1067\/mod.2002.123036"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2007.05.018"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2013.10.022"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1067\/mod.2002.127320"},{"issue":"10","key":"e_1_2_5_21_1","first-page":"544","article-title":"The Readers' Corner. 2. What percentage of your patients are being treated with Invisalign appliances?","volume":"38","author":"Sheridan JJ","year":"2004","journal-title":"J Clin Orthod"},{"key":"e_1_2_5_22_1","volume-title":"The Invisalign Reference Guide","author":"Inc. AT","year":"2002"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.2319\/0003-3219(2008)078[0682:IOAAIR]2.0.CO;2"}],"container-title":["Journal of Investigative and Clinical Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjicd.12455","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jicd.12455","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jicd.12455","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jicd.12455","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T21:08:19Z","timestamp":1693948099000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jicd.12455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,2]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/jicd.12455"],"URL":"https:\/\/doi.org\/10.1111\/jicd.12455","archive":["Portico"],"relation":{},"ISSN":["2041-1618","2041-1626"],"issn-type":[{"value":"2041-1618","type":"print"},{"value":"2041-1626","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,2]]},"assertion":[{"value":"2019-05-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12455"}}