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The current study examined the impact of family environmental characteristics on social\u2010behavioural and cognitive outcomes in this paediatric population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Guardians of children with 22q11<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> were recruited through two medical genetics clinics. Consenting guardians were asked to complete several questionnaires regarding their child's social, emotional and behavioural functioning, as well as family social environment and parenting styles. Children with 22q11<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> were asked to undergo a cognitive assessment, including <jats:styled-content style=\"fixed-case\">IQ<\/jats:styled-content> and achievement testing, and measures of attention, executive function and memory.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Modest associations were found between aspects of the family social environment and parenting styles with social\u2010behavioural and cognitive\/academic outcomes. Regression models indicated that physical punishment, socioeconomic status, parental control and family organisation significantly predicted social\u2010behavioural and cognitive outcomes in children with 22q11<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Characteristics of the family social environment and parenting approaches appear to be associated with functional outcomes of children with 22q11<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content>. Understanding the impact of environmental variables on developmental outcomes can be useful in determining more effective targets for intervention. This will be important in order to improve the quality of life of individuals affected by 22q11<jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jir.12054","type":"journal-article","created":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T10:15:36Z","timestamp":1370600136000},"page":"31-47","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Association of the family environment with behavioural and cognitive outcomes in children with chromosome 22q11.2 deletion syndrome"],"prefix":"10.1111","volume":"58","author":[{"given":"T. M.","family":"Allen","sequence":"first","affiliation":[{"name":"Department of Psychology &amp; Neuroscience Duke University  Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Hersh","sequence":"additional","affiliation":[{"name":"Department of Psychology &amp; Neuroscience Duke University  Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Schoch","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Medical Genetics Duke University Medical Center  Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Curtiss","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Division of Medical Genetics Duke University Medical Center  Durham NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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