{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T10:47:27Z","timestamp":1787827647256,"version":"build-2784847793"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,4,25]],"date-time":"2014-04-25T00:00:00Z","timestamp":1398384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J intellect Disabil Res"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The administration of oral medication to patients with an enteral feeding tube (<jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content>) is challenging. Compliance to guidelines concerning medication administration via <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> has been investigated extensively in the hospital setting. However, studies in residential care facilities (<jats:styled-content style=\"fixed-case\">RCFs<\/jats:styled-content>) for individuals with intellectual disability (<jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content>) are very limited. Therefore, the present study aimed to collect direct observational data on drug administration practices to residents with <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> in multiple <jats:styled-content style=\"fixed-case\">RCFs<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This cross\u2010sectional, observational study was conducted in six Belgian <jats:styled-content style=\"fixed-case\">RCFs<\/jats:styled-content> for individuals with <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content>. Observations of medication preparation and administration through <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> were carried out in two randomly selected units per participating <jats:styled-content style=\"fixed-case\">RCF<\/jats:styled-content>, on 2 days per unit during all daytime drug rounds, using a direct observation method. Afterwards, the recorded observations were compared with international guidelines on drug preparation and administration through <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 862 drug preparations and 268 administrations in 48 residents with <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> were witnessed. Mixing together multiple drugs, not diluting liquid formulations with at least an equal amount of water, not shaking suspensions\/emulsions before use, and not selecting the most appropriate dosage form were the most common deviations from medication preparation guideline recommendations. For medication administration, not flushing the <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> with at least 15\u2009mL water was the most common deviation. We also observed high variability in working methods regarding medication preparation and administration via <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content>, even between staff members of the same unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study found that current guidelines concerning medication preparation and administration through <jats:styled-content style=\"fixed-case\">EFT<\/jats:styled-content> are often not followed in <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>elgian <jats:styled-content style=\"fixed-case\">RCFs<\/jats:styled-content> for individuals with <jats:styled-content style=\"fixed-case\">ID<\/jats:styled-content>. Further research aimed at understanding why current guidelines are not followed seems warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jir.12129","type":"journal-article","created":{"date-parts":[[2014,4,25]],"date-time":"2014-04-25T10:07:31Z","timestamp":1398420451000},"page":"215-225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Drug administration via enteral feeding tubes in residential care facilities for individuals with intellectual disability: an observational study"],"prefix":"10.1111","volume":"59","author":[{"given":"E.","family":"Joos","sequence":"first","affiliation":[{"name":"Pharmaceutical Care Unit Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Mehuys","sequence":"additional","affiliation":[{"name":"Pharmaceutical Care Unit Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Van Bocxlaer","sequence":"additional","affiliation":[{"name":"Department of Bioanalysis Ghent University  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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