{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:18:26Z","timestamp":1790360306772,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J intellect Disabil Res"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adults with intellectual disabilities (IDs) face significant health inequalities and reduced life expectancy compared to the general population. Sleep disorders, including obstructive sleep apnoea (OSA), are highly prevalent in this population; however, standard diagnostic modalities may be poorly tolerated and many people may remain undiagnosed. The aim of this study was to assess the feasibility of using an acoustic\u2010derived home\u2010based sleep study to diagnose OSA in adults with ID who were unable to tolerate standard inpatient or home sleep studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>This was a prospective feasibility study (GSTT\/2024\/15803). Participants were identified from two tertiary outpatient sleep departments in London, UK. Eligible participants were aged \u2265 17\u2009years with a diagnosed ID. Inpatient or existing home studies had not been tolerated or had been declined. Participants wore a small diagnostic sensor, the AcuPebble SA100 (Acurable Ltd., London, UK) for one to two nights in their own home. Baseline symptom screening and quality of life questionnaires were administered. Semiqualitative and qualitative feedback was obtained from participants. The primary outcome was successful completion of testing, defined as \u2265 240\u2009min of recording on at least one night. Quantitative diagnostic parameters were reviewed in a multidisciplinary team (MDT) meeting to formulate a management plan. Data are presented as mean (standard deviation), unless otherwise specified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seventeen people were screened, and 10 agreed to participate in the study (3F\/7M). Eight participants (80%) successfully completed testing (2F\/6M, 4 severe ID, age 29.7 [15.4] years, body mass index, BMI 27.1 [5.9] kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , apnoea hypopnoea index, median AHI 5.5 [IQR 7.8] ev\/h). Of these, five participants (63%) were found to have OSA. Feedback was favourable with an average total satisfaction score of 14.0 (4.8) out of 20 points.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In a cohort of participants with ID who were unable to tolerate standard sleep diagnostics to assess OSA, an acoustic\u2010derived home\u2010based sleep study may provide a solution to achieve clinically diagnostic recordings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jir.70000","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T03:03:47Z","timestamp":1749611027000},"page":"1215-1223","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acoustics\u2010Derived Home\u2010Based Sleep Study for the Diagnosis of Obstructive Sleep Apnoea in Adults With Intellectual Disabilities: A Feasibility Study"],"prefix":"10.1111","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8337-2357","authenticated-orcid":false,"given":"Lachlan","family":"Stranks","sequence":"first","affiliation":[{"name":"Sleep Disorders Centre &amp; Lane Fox Unit Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Abdulsalam","sequence":"additional","affiliation":[{"name":"Department of Sleep and Respiratory Failure Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3809-022X","authenticated-orcid":false,"given":"David","family":"O'Regan","sequence":"additional","affiliation":[{"name":"Sleep Disorders Centre &amp; Lane Fox Unit Guy's and St Thomas' NHS Foundation Trust  London UK"},{"name":"Faculty of Life Sciences and Medicine King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1587-3109","authenticated-orcid":false,"given":"Joerg","family":"Steier","sequence":"additional","affiliation":[{"name":"Sleep Disorders Centre &amp; Lane Fox Unit Guy's and St Thomas' NHS Foundation Trust  London UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), Faculty of Life Sciences and Medicine King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alanna","family":"Hare","sequence":"additional","affiliation":[{"name":"Department of Sleep and Respiratory Failure Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,11]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"The International Classification of Sleep Disorders \u2013 Third Edition (ICSD\u20103)","author":"AASM","year":"2014"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2012.02255.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0232596"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31816d83e4"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-046803"},{"issue":"7","key":"e_1_2_10_7_1","first-page":"499","article-title":"Nonverbal Patient With Autism Spectrum Disorder and Obstructive Sleep Apnea: Use of Desensitization to Acclimatize to a Dental Appliance","volume":"36","author":"Fetner M.","year":"2014","journal-title":"Pediatric Dentistry"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.136879"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.7382"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jir.12314"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-011-9903-x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2014.01.022"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-022-01218-7"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62026-7"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2019.10.003"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2016.303240"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.1.30"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjb.2021.122"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14-0266"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.10626"},{"issue":"8","key":"e_1_2_10_21_1","first-page":"1079","article-title":"Sleep Apnea as an Independent Risk Factor for All\u2010Cause Mortality: The Busselton Health Study","volume":"31","author":"Marshall N. S.","year":"2008","journal-title":"Sleep"},{"key":"e_1_2_10_22_1","unstructured":"NICE.2024.Home\u2010Testing Devices for Diagnosing Obstructive Sleep Apnoea Hypopnoea Syndrome. NICE Guideline National Institute for Health and Care Excellence. DG62."},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax-2023-220032"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13020571"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bld.12480"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.2147\/NSS.S154723"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2013-004606"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2012.03.003"}],"container-title":["Journal of Intellectual Disability Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jir.70000","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T08:09:13Z","timestamp":1761898153000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jir.70000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,11]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["10.1111\/jir.70000"],"URL":"https:\/\/doi.org\/10.1111\/jir.70000","archive":["Portico"],"relation":{},"ISSN":["0964-2633","1365-2788"],"issn-type":[{"value":"0964-2633","type":"print"},{"value":"1365-2788","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,11]]},"assertion":[{"value":"2024-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}