{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:41:20Z","timestamp":1792374080307,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:00:00Z","timestamp":1792281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:00:00Z","timestamp":1792281600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J intellect Disabil Res"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Speech, language and communication needs (SLCN) are frequently reported in KBG syndrome yet no study has investigated them using standardised assessments. This study aimed to characterise the communicative abilities of children with KBG syndrome using a combination of caregiver\u2010reported questionnaires and adapted online speech and language assessments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Sixteen UK and US families of children with KBG syndrome (aged 3\u201314\u2009years old) took part. In phase 1 of the study, caregivers (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200916) completed online questionnaires about the child's medical and developmental history, communication ability and adaptive behaviour. In phase 2 of the study, children (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200910) completed adapted online assessments of speech sound skills, oro\u2010motor function, morphosyntactic ability, receptive vocabulary and sentence comprehension. Six families did not complete phase 2 due to attrition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All of the 16 children included were reported to communicate using sentences. Caregiver\u2010reported data revealed that 12\/12 children assessed using the Child Communication Checklist\u20102 had significant communication challenges and 12\/13 assessed using the Vineland Adaptive Behaviour Scales experienced differences in adaptive behaviour compared with typically developing children. Among the children assessed directly, 7\/10 had speech sound skills that were not age\u2010appropriate and 7\/9 exhibited oro\u2010motor difficulties. Six out of 10 children had lower than average receptive vocabulary, 5\/10 had lower than average sentence comprehension and 5\/8 had lower than average morphosyntactic processing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings indicate that SLCN are important phenotypic features of KBG syndrome, with speech and oro\u2010motor difficulties appearing to be particularly pervasive. This underscores the need to prioritise the assessment and monitoring of SLCN in children with KBG syndrome to provide opportunity for early and targeted intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jir.70192","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:33:56Z","timestamp":1792373636000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Speech, Language and Communication in Children With KBG Syndrome"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9590-6144","authenticated-orcid":false,"given":"Harriet","family":"Smith","sequence":"first","affiliation":[{"name":"University of Sheffield  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0534-9095","authenticated-orcid":false,"given":"Megan","family":"Freeth","sequence":"additional","affiliation":[{"name":"University of Sheffield  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2706-121X","authenticated-orcid":false,"given":"Silke","family":"Fricke","sequence":"additional","affiliation":[{"name":"University of Sheffield  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3562-9549","authenticated-orcid":false,"given":"Danielle","family":"Matthews","sequence":"additional","affiliation":[{"name":"University of Sheffield  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Lea","sequence":"additional","affiliation":[{"name":"Sheffield Children's Hospital NHS Foundation Trust  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5702-3631","authenticated-orcid":false,"given":"Alisdair","family":"McNeill","sequence":"additional","affiliation":[{"name":"University of Sheffield  Sheffield UK"},{"name":"Sheffield Children's Hospital NHS Foundation Trust  Sheffield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,18]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1357633X221124998"},{"key":"e_1_2_12_3_1","unstructured":"Anderson A.2014. \u201cWeb\u2010Based Telerehabilitation Assessment of Receptive Language (Master's Thesis).\u201d Washington State University Spokane United State."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1044\/2023_AJSLP\u201022\u201000172"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gim.2024.101170"},{"key":"e_1_2_12_6_1","volume-title":"The Children's Communication Checklist: CCC\u20102","author":"Bishop D. 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