{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T17:08:47Z","timestamp":1765040927812,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T00:00:00Z","timestamp":1562544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Japan Journal Nursing Sci"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>There is increasing evidence that hyperglycemia, oxidative stress, and the accumulation of advanced glycation end products in type 2 diabetes mellitus (T2DM) can lead to the deterioration of bone remodeling. The purpose of this study was to explore relationships of social support, health\u2010promoting lifestyles, glycated hemoglobin (HbA1c) levels, and serum bone turnover markers (BTMs, including procollagen type I amino\u2010terminal propeptide [PINP] and \u03b2\u2010isomerised carboxy\u2010terminal cross\u2010linking telopeptide of type I collagen [\u03b2\u2010CTX]) among individuals with T2DM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 175 subjects were recruited by convenience sampling and divided into three groups based on their HbA1c levels. Statistical strategies of Spearman's correlation coefficient and multiple linear regression were used in this cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a positive association between PINP and \u03b2\u2010CTX, whereas the HbA1c level was inversely correlated with BTMs. Moreover, scores of both PINP and \u03b2\u2010CTX were different in genders, males having lower levels of BTMs than females after adjustment for weight. Furthermore, both social support and health\u2010promoting lifestyles were negatively correlated with HbA1c levels, whereas they did not significantly relate to declines in PINP and \u03b2\u2010CTX.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>High HbA1c levels detrimentally influence bone formation and bone resorption, and males with T2DM might be more susceptible to osteoporosis because of their relatively lower levels of BTMs. However, <jats:bold>s<\/jats:bold>ocial support and health\u2010promoting lifestyles could contribute to better glycemic control.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jjns.12280","type":"journal-article","created":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T01:23:37Z","timestamp":1562635417000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationships of social support, health\u2010promoting lifestyles, glycemic control, and bone turnover among adults with type 2 diabetes"],"prefix":"10.1111","volume":"17","author":[{"given":"Mei","family":"Ha","sequence":"first","affiliation":[{"name":"School of Nursing Chongqing Medical and Pharmaceutical College  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Chen","sequence":"additional","affiliation":[{"name":"Chenjiaqiao Hospital, the Affiliated Hospital of Chongqing Medical and Pharmaceutical College  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Nursing Chongqing Medical and Pharmaceutical College  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"School of Nursing Chongqing Medical and Pharmaceutical College  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changjiang","family":"Liu","sequence":"additional","affiliation":[{"name":"NHC Key Laboratory of Birth Defects and Reproductive Health Chongqing Population and Family Planning Science and Technology Research Institute  Chongqing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S32745"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2015.03.014"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-3361"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2109542"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc17-2144"},{"key":"e_1_2_9_7_1","first-page":"286","article-title":"Development and psychometric tests of a Chinese version of the HPLP\u2010II scales","volume":"20","author":"Cao W. 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