{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T17:59:55Z","timestamp":1787162395021,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,9]],"date-time":"2020-02-09T00:00:00Z","timestamp":1581206400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17H06645"],"award-info":[{"award-number":["17H06645"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Japan Journal Nursing Sci"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Following chemotherapy, induration may occur. This study was conducted to survey induration incidence and risk factors, and investigation for actual condition of induration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cohort study was conducted for survey of incidence and risk factors, and a cross\u2010sectional observation study was conducted to examine actual condition of induration. The sites of chemotherapy administration were recorded, and these were observed on the next treatment day. Clinical nurses judged the presence or absence of induration by palpation. The sites were observed using ultrasonography. To investigate the risk factors associated with the induration, logistic regression analysis was performed using independent variables based on univariate analysis or previous reports.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 69 patients were analyzed. The induration incidence was 17.4%, and three abnormal conditions were confirmed: subcutaneous edema, thrombosis, and thickening of the vessel wall. Breast cancer, non\u2010vesicant drug, vein diameter, and fosaprepitant use were included in the logistic regression model. Breast cancer: odds ratio (OR) 9.25; 95 CI 1.91.\u201344.71; non\u2010vesicant drug: OR 1.37; 95 CI 0.13\u201314.95; vein diameter: OR 0.40; 95% CI 0.16\u20130.97; fosaprepitant use: OR 0.16; 95% CI, 0.18\u201310.32.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The induration incidence was 17.4%. Risk factors for induration following chemotherapy administration were breast cancer and smaller vein diameter. Abnormal cases of subcutaneous tissue were confirmed, including subcutaneous edema, thrombosis, and thickening of the vessel wall. Induration may be prevented by selecting larger diameter vessels using ultrasonography when catheterizing for chemotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jjns.12329","type":"journal-article","created":{"date-parts":[[2020,2,9]],"date-time":"2020-02-09T21:49:32Z","timestamp":1581284972000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Incidence, risk factors, and assessment of induration by ultrasonography after chemotherapy administration through a peripheral intravenous catheter"],"prefix":"10.1111","volume":"17","author":[{"given":"Mari","family":"Abe\u2010Doi","sequence":"first","affiliation":[{"name":"Department of Advanced Nursing Technology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoko","family":"Murayama","sequence":"additional","affiliation":[{"name":"Department of Advanced Nursing Technology, Graduate School of Medicine The University of Tokyo  Tokyo Japan"},{"name":"Global Nursing Research Center, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieko","family":"Komiyama","sequence":"additional","affiliation":[{"name":"Department of Nursing The University of Tokyo Hospital  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1912-1251","authenticated-orcid":false,"given":"Hiromi","family":"Sanada","sequence":"additional","affiliation":[{"name":"Global Nursing Research Center, Graduate School of Medicine The University of Tokyo  Tokyo Japan"},{"name":"Department of Gerontological Nursing\/Wound Care Management, Graduate School of Medicine The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,9]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"American Cancer Society.Breast Cancer Facts & Figures 2017\u20132018. Atlanta: American Cancer Society Inc.;2017. Retrieved fromhttps:\/\/www.cancer.org\/content\/dam\/cancer\u2010org\/research\/cancer\u2010facts\u2010and\u2010statistics\/breast\u2010cancer\u2010facts\u2010and\u2010figures\/breast\u2010cancer\u2010facts\u2010and\u2010figures\u20102017\u20102018.pdf"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0b013e3181aac042"},{"key":"e_1_2_9_4_1","unstructured":"Extravasation Guidelines. (2008).European Oncology Nursing Society of Clinical Guidelines. Retrieved fromhttps:\/\/www.cancernurse.eu\/documents\/EONSClinicalGuidelinesSection6-en.pdf"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.31.7859"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.NAJ.0000282299.03441.c7"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2011.10.028"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5507-y"},{"issue":"4","key":"e_1_2_9_9_1","first-page":"438","article-title":"Chemotherapy extravasation: Establishing a National Benchmark for Incidence Among Cancer Centers","volume":"21","author":"Jackson\u2010Rose J.","year":"2017","journal-title":"Clinical Journal of Oncology Nursing"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-21002010000400017"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2019.01064"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000001248"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2017.02.009"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds294"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-014-2535-2"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.05.055"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/NAN.0000000000000159"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2003000900002"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/674398"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2017.02.009"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2008.07.003"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmu.2016.02.001"},{"issue":"1","key":"e_1_2_9_23_1","first-page":"40","article-title":"Ultrasonographic appearance of infusion via the peripheral intravenous catheters","volume":"2","author":"Yabunaka K.","year":"2015","journal-title":"Journal of Nursing Science and Engineering"},{"issue":"1","key":"e_1_2_9_24_1","first-page":"43","article-title":"Study on the infusion site adverse events and vascular distribution of epirubicin in chemotherapy with epirubicin and fosaprepitant","volume":"11","author":"Yamasaki M.","year":"2019","journal-title":"Molecular and Clinical Oncology"}],"container-title":["Japan Journal of Nursing Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jjns.12329","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jjns.12329","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jjns.12329","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T00:15:35Z","timestamp":1693872935000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jjns.12329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,9]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/jjns.12329"],"URL":"https:\/\/doi.org\/10.1111\/jjns.12329","archive":["Portico"],"relation":{},"ISSN":["1742-7932","1742-7924"],"issn-type":[{"value":"1742-7932","type":"print"},{"value":"1742-7924","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,9]]},"assertion":[{"value":"2019-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12329"}}