{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T07:30:20Z","timestamp":1787815820912,"version":"build-2784847793"},"reference-count":56,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Japan Journal Nursing Sci"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A systematic review and meta\u2010analysis was conducted to evaluate the effectiveness of mobile applications used by patients diagnosed with mental disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An electronic literature search in five databases including PubMed, Embase, the Cochrane Library, CINAHL, and PsychInfo was conducted. The keywords used were \u201cmental disorder,\u201d \u201cmental illness,\u201d \u201cmobile phone,\u201d \u201csmartphone,\u201d \u201cmHealth,\u201d \u201capplication,\u201d and \u201capp\u201d. The search was restricted to randomized controlled trials (RCTs) written in English and Korean.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen RCTs, involving 1307 patients diagnosed with depression, schizophrenia, and bipolar disorder were included in the analysis. The included studies were published between 2012 and 2020 and used mobile applications. The risk of bias tool was used to assess methodological quality and the overall risk of bias of the included studies was moderate. The pooled data favored mobile application interventions in reducing the disease\u2010related symptoms of depression (standardized mean difference [SMD]\u00a0=\u00a0\u22120.255, 95% CI: \u22120.370 to \u22120.141), mania symptoms (SMD\u00a0=\u00a0\u22120.279, 95% CI: \u22120.456 to \u22120.102), and positive (SMD\u00a0=\u00a0\u22120.205, 95% CI: \u22120.388 to \u22120.022) and negative psychotic symptoms (SMD\u00a0=\u00a0\u22120.406, 95% CI: \u22120.791 to \u22120.020). In subgroup analysis, the incorporation of feedback, notification, and data tracking features in the mobile application intervention produced better outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This review provided evidence that mobile applications could well\u2010assist patients diagnosed with mental disorders. Greater benefits could be achieved by well\u2010designed interventions incorporating strategies with thoughtful consideration of the disease characteristics. Mobile applications present the potential to be effective supplements to clinical treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jjns.12476","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T10:53:02Z","timestamp":1645095182000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Effectiveness of mobile applications for patients with severe mental illness: A meta\u2010analysis of randomized controlled trials"],"prefix":"10.1111","volume":"19","author":[{"given":"Sun Kyung","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Nursing, and Department of Biomedicine, Health &amp; Life Convergence Sciences, BK21 Four, Biomedical and Healthcare Research Institute Mokpo National University  Muan\u2010gun South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5700-3534","authenticated-orcid":false,"given":"Mihyun","family":"Lee","sequence":"additional","affiliation":[{"name":"College of Nursing Daejeon Health Institute of Technology  Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8699-4023","authenticated-orcid":false,"given":"Hyun","family":"Jeong","sequence":"additional","affiliation":[{"name":"College of Nursing Daejeon Health Institute of Technology  Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Mi","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Nursing Daejeon Institute of Science and Technology  Daejeon South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.20f13681"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2012.05.007"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20151"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(18)30302-X"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.2196\/mental.4984"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/MDER.S144158"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2019.10.026"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbu033"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201800063"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-20852-7_11"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-017-0848-9"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2007.10.004"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.janxdis.2014.02.003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2196\/18818"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ja.2014.10.053"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sby135"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.2791"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291715000410"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/ebmental-2019-300106"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.4930"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.04.046"},{"issue":"2","key":"e_1_2_9_23_1","first-page":"130","article-title":"How to identify randomized controlled trials in MEDLINE: Ten years on","volume":"94","author":"Glanville J. 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