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Until recently, such testing was only plausible in the context of a family history of a Mendelian condition that might prompt the parents (or an adolescent) to request testing for the adult-onset condition present within the family. In this context there has been a gradual shift in the direction of suggesting parents should have greater discretion to obtain such testing after careful consideration of risks and benefits by the family and the health care provider.<\/jats:p>","DOI":"10.1111\/jlme.12298","type":"journal-article","created":{"date-parts":[[2021,1,25]],"date-time":"2021-01-25T02:53:44Z","timestamp":1611543224000},"page":"552-558","source":"Crossref","is-referenced-by-count":53,"title":["Disclosing Secondary Findings from Pediatric Sequencing to Families: Considering the \u201cBenefit to Families\u201d"],"prefix":"10.1017","volume":"43","author":[{"given":"Benjamin S.","family":"Wilfond","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conrad V.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert C.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"56","published-online":{"date-parts":[[2021,1,1]]},"reference":[{"key":"S1073110500019483_bib4","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2014.151"},{"key":"S1073110500019483_bib19","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320540304"},{"key":"S1073110500019483_bib28","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-0553"},{"key":"S1073110500019483_bib26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1312543"},{"key":"S1073110500019483_bib3","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2013.73"},{"key":"S1073110500019483_bib8","first-page":"1233","article-title":"\u201cPoints to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents,\u201d","volume":"57","year":"1995","journal-title":"American Journal of Human Genetics"},{"key":"S1073110500019483_bib1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5201509"},{"key":"S1073110500019483_bib5","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2013.113"},{"key":"S1073110500019483_bib27","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-015-0132-8"},{"key":"S1073110500019483_bib13","first-page":"431","article-title":"\u201cPerception of Carrier Status by Cystic Fibrosis Siblings,\u201d","volume":"57","author":"Fanos","year":"1995","journal-title":"American Journal of Human Genetics"},{"key":"S1073110500019483_bib2","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsn075"},{"key":"S1073110500019483_bib12","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e3181de695c"},{"key":"S1073110500019483_bib23","doi-asserted-by":"publisher","DOI":"10.1007\/s11017-004-3146-6"},{"key":"S1073110500019483_bib9","doi-asserted-by":"publisher","DOI":"10.2307\/3527620"},{"key":"S1073110500019483_bib18","doi-asserted-by":"crossref","DOI":"10.1515\/9780691218144","volume-title":"Freedom and Fulfillment","author":"Feinberg","year":"1992"},{"key":"S1073110500019483_bib24","unstructured":"24. 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