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Eighteen reports from 17 studies were included, covering quantitative, qualitative, and mixed\u2010methods designs. Quantitative findings showed that multi\u2010family therapy was more consistently associated with improvements in individual\u2010level outcomes (e.g., symptom severity, psychological distress, functioning), whereas effects on family\u2010system outcomes were more mixed. Thematic synthesis of qualitative and mixed\u2010methods studies identified four interrelated themes: multi\u2010family therapy creates a non\u2010problem\u2010saturated space for families to come together; engages them in fun activities; fosters inter\u2010 and intra\u2010family connection; and supports relational understanding. Overall, individual\u2010level benefits are more readily captured by quantitative measures, while relational and process\u2010level changes may be less well\u2010reflected. Future research should strengthen methodological rigor and extend multi\u2010family therapy to presenting problems, such as eating disorders, to better evaluate its family\u2010system mechanisms and effects<\/jats:p>","DOI":"10.1111\/jmft.70166","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T08:58:08Z","timestamp":1787129888000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi\u2010Family Therapy in East and Southeast Asia\u2014A Systematic Review and Meta\u2010Synthesis"],"prefix":"10.1111","volume":"52","author":[{"given":"Ouyang","family":"Hanlai","sequence":"first","affiliation":[{"name":"Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine and School of Psychology Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sufang","family":"Peng","sequence":"additional","affiliation":[{"name":"Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine and School of Psychology Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9924-2573","authenticated-orcid":false,"given":"Jue","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine and School of Psychology Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2241-1017","authenticated-orcid":false,"given":"See Heng","family":"Yim","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Hong Kong HKSAR China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","DOI":"10.4324\/9781003442424","volume-title":"Systemic Multi\u2010Family Therapy: Concepts and Interventions","author":"Asen E.","year":"2024"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4324\/9780203841143"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-9-59"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/eat.23616"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/erv.3050"},{"key":"e_1_2_10_7_1","unstructured":"Burg J. 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