{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:15:22Z","timestamp":1758759322276,"version":"3.44.0"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T00:00:00Z","timestamp":1747958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFE0108800"],"award-info":[{"award-number":["2023YFE0108800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62175020"],"award-info":[{"award-number":["62175020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Microscopy"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Influenza B virus and SARS\u2010CoV\u20102 virus are the two most representative respiratory infectious diseases. These two viruses not only show similarities in clinical symptoms but also have numerous similarities in microstructure, which is difficult to distinguish and poses great challenges for diagnosis. In this work, the three\u2010dimensional structures and surface features of influenza B virus and SARS\u2010CoV\u20102 virus were investigated using atomic force microscopy. The results indicated that there were substantial differences in surface morphology and structure between the two viruses. Specifically, the average diameter of SARS\u2010CoV\u20102 virus particles was around 222.8 nm while that of influenza B virus particles is smaller at about 191.2 nm. The height of SARS\u2010CoV\u20102 particles was also larger, averaging about 30\u201360 nm, while that of influenza B virus particles averaged around 10\u201330 nm. Additionally, the crown\u2010like structure on the surface of the SARS\u2010CoV\u20102 virus was sparser and more prominent than that of the influenza virus. These findings offer significant insights into the distinction between the two viruses, aiding in the accurate characterisation of SARS\u2010CoV\u20102 and influenza viruses and facilitating timely and effective treatment strategies.<\/jats:p>","DOI":"10.1111\/jmi.13432","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T06:27:15Z","timestamp":1747981635000},"page":"27-35","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative morphological characterisation of SARS\u2010CoV\u20102 and influenza B virus using atomic force microscopy"],"prefix":"10.1111","volume":"300","author":[{"given":"Junru","family":"Wang","sequence":"first","affiliation":[{"name":"International Research Centre for Nano Handling and Manufacturing of China Changchun University of Science and Technology Changchun China"},{"name":"Centre for Opto\/Bio\u2010Nano Measurement and Manufacturing Zhongshan 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Education Key Laboratory for Cross\u2010Scale Micro and Nano Manufacturing Changchun University of Science and Technology Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyu","family":"Wang","sequence":"additional","affiliation":[{"name":"International Research Centre for Nano Handling and Manufacturing of China Changchun University of Science and Technology Changchun China"},{"name":"Centre for Opto\/Bio\u2010Nano Measurement and Manufacturing Zhongshan Institute of Changchun University of Science and Technology Zhongshan China"},{"name":"Ministry of Education Key Laboratory for Cross\u2010Scale Micro and Nano Manufacturing Changchun University of Science and Technology Changchun China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junxi","family":"Wang","sequence":"additional","affiliation":[{"name":"International Research Centre for Nano Handling and Manufacturing of China Changchun University of Science and Technology Changchun 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