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Feasibility of culturing 0.9<jats:styled-content style=\"fixed-case\">G<\/jats:styled-content> fetal baboon hepatocytes was demonstrated. <jats:styled-content style=\"fixed-case\">PEPCK<\/jats:styled-content>\u20101 protein levels were increased in hepatocytes isolated from <jats:styled-content style=\"fixed-case\">IUGR<\/jats:styled-content> fetuses, and <jats:styled-content style=\"fixed-case\">PEPCK<\/jats:styled-content>\u20101 m<jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content> expression was stimulated by glucocorticoids in fetal hepatocytes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cultured fetal baboon hepatocytes that retain their <jats:italic>in vivo<\/jats:italic> phenotype provide powerful <jats:italic>in vitro<\/jats:italic> tools to investigate mechanisms that regulate normal and programmed hepatic function.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12048","type":"journal-article","created":{"date-parts":[[2013,4,20]],"date-time":"2013-04-20T05:02:55Z","timestamp":1366434175000},"page":"211-219","source":"Crossref","is-referenced-by-count":16,"title":["Effects of maternal nutrient restriction, intrauterine growth restriction, and glucocorticoid exposure on phosphoenolpyruvate carboxykinase\u20101 expression in fetal baboon hepatocytes <i>in vitro<\/i>"],"prefix":"10.1111","volume":"42","author":[{"given":"Cun","family":"Li","sequence":"first","affiliation":[{"name":"Center for Pregnancy and Newborn Research University of Texas Health Science Center San Antonio TX USA"},{"name":"Department of Obstetrics and Gynecology University of Texas Health Science Center San Antonio TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen\u2010Ju","family":"Shu","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Texas Health Science Center San Antonio TX USA"},{"name":"Geriatric Research, Education and Clinical Center Audie L. Murphy Division South Texas Veterans Health Care System San Antonio TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuko","family":"Lee","sequence":"additional","affiliation":[{"name":"Research Service Audie L. Murphy Division South Texas Veterans Health Care System San Antonio TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhulika B.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Departments of Pediatrics and Biochemistry University of Western Ontario London ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Jansson","sequence":"additional","affiliation":[{"name":"Center for Pregnancy and Newborn Research University of Texas Health Science Center San Antonio TX USA"},{"name":"Department of Obstetrics and Gynecology University of Texas Health Science Center San Antonio TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter W.","family":"Nathanielsz","sequence":"additional","affiliation":[{"name":"Center for Pregnancy and Newborn Research University of Texas Health Science Center San Antonio TX USA"},{"name":"Department of Obstetrics and Gynecology University of Texas Health Science Center San Antonio TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amrita","family":"Kamat","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Texas Health Science Center San Antonio TX USA"},{"name":"Geriatric Research, Education and Clinical Center Audie L. 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