{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T17:34:41Z","timestamp":1788888881436,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T00:00:00Z","timestamp":1508803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1060424"],"award-info":[{"award-number":["OPP1060424"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1084270"],"award-info":[{"award-number":["OPP1084270"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1118762"],"award-info":[{"award-number":["OPP1118762"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P51 RR000163"],"award-info":[{"award-number":["P51 RR000163"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P51 RR013986"],"award-info":[{"award-number":["P51 RR013986"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We evaluated whether menstrual cycle phase influences the assessment of tubal patency by hysterosalpingography (<jats:styled-content style=\"fixed-case\">HSG<\/jats:styled-content>) in baboons.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of baseline tubal patency studies and serum estradiol (E<jats:sub>2<\/jats:sub>) and progesterone (P4) values obtained from female baboons used as models for development of non\u2010surgical permanent contraception in women. The main outcome measure was bilateral tubal patency (<jats:styled-content style=\"fixed-case\">BTP<\/jats:styled-content>) in relationship with estradiol level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Female baboons (n\u00a0=\u00a0110) underwent a single (n\u00a0=\u00a081), two (n\u00a0=\u00a026), or three (n\u00a0=\u00a03) <jats:styled-content style=\"fixed-case\">HSG<\/jats:styled-content> examinations. In 33\/142 (23%) <jats:styled-content style=\"fixed-case\">HSG<\/jats:styled-content> examinations, one or both tubes showed functional occlusion (<jats:styled-content style=\"fixed-case\">FO<\/jats:styled-content>). The median E<jats:sub>2<\/jats:sub> in studies with <jats:styled-content style=\"fixed-case\">BTP<\/jats:styled-content> (49\u00a0pg\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>) was significantly higher than in those studies with <jats:styled-content style=\"fixed-case\">FO<\/jats:styled-content> (32\u00a0pg\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>,<jats:italic> P<\/jats:italic>\u00a0=\u00a0.005). Among 18 animals with repeat examinations where serum E<jats:sub>2<\/jats:sub> changed from &lt;60 to \u2265 60\u00a0pg\/<jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>, 13 results changed from <jats:styled-content style=\"fixed-case\">FO<\/jats:styled-content> to <jats:styled-content style=\"fixed-case\">BTP<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0001). No sets showed a change from <jats:styled-content style=\"fixed-case\">BTP<\/jats:styled-content> to <jats:styled-content style=\"fixed-case\">FO<\/jats:styled-content> with an increase in estradiol.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In baboons, functional occlusion of the fallopian tube is associated with low estradiol levels, supporting a role for estrogen\u2010mediated relaxation of the utero\u2010tubal junction.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12317","type":"journal-article","created":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T08:12:47Z","timestamp":1508832767000},"page":"40-45","source":"Crossref","is-referenced-by-count":3,"title":["Effect of menstrual cycle phase and hormonal treatments on evaluation of tubal patency in baboons"],"prefix":"10.1111","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4733-1224","authenticated-orcid":false,"given":"Jeffrey T.","family":"Jensen","sequence":"first","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Oregon Health &amp; Science University (OHSU)  Portland OR USA"},{"name":"Division of Reproductive and Developmental Sciences Oregon National Primate Research Center  Beaverton OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Hanna","sequence":"additional","affiliation":[{"name":"Division of Reproductive and Developmental Sciences Oregon National Primate Research Center  Beaverton OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Mishler","sequence":"additional","affiliation":[{"name":"Division of Reproductive and Developmental Sciences Oregon National Primate Research Center  Beaverton OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong Y.","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Oregon Health &amp; Science University (OHSU)  Portland OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ov D.","family":"Slayden","sequence":"additional","affiliation":[{"name":"Division of Reproductive and Developmental Sciences Oregon National Primate Research Center  Beaverton OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,24]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1","volume-title":"Practice Parameter","author":"American College of Radiology","year":"2014"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.157.1.1675547"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh111"},{"key":"e_1_2_7_5_1","first-page":"205","article-title":"Tubal patency in hysterosalpingography during the various phases of the menstrual cycle","volume":"150","author":"Lindahl J","year":"1960","journal-title":"Gynaecologia"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2008.02.010"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2007.01351.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2016.07.008"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2015.06.002"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2016.03.006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.contraception.2015.06.007"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000101739"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000177"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-06-0266"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)59413-8"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod29.5.1289"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)45736-5"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)44238-X"},{"key":"e_1_2_7_19_1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1177\/0284185116679457","article-title":"Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives: a pilot study in women","volume":"58","author":"Jensen JT","year":"2017","journal-title":"Acta Radiol"}],"container-title":["Journal of Medical Primatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjmp.12317","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jmp.12317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T21:39:47Z","timestamp":1695850787000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jmp.12317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,24]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1111\/jmp.12317"],"URL":"https:\/\/doi.org\/10.1111\/jmp.12317","archive":["Portico"],"relation":{},"ISSN":["0047-2565","1600-0684"],"issn-type":[{"value":"0047-2565","type":"print"},{"value":"1600-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,24]]}}}