{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T19:02:21Z","timestamp":1781290941757,"version":"3.54.1"},"reference-count":42,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T00:00:00Z","timestamp":1525046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"BK21 PLUS Program for Creative Veterinary Science Research"},{"name":"The Research Institute of Veterinary Science"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Toxoplasma gondii<\/jats:italic> (<jats:italic>T.\u00a0gondii<\/jats:italic>) is an intracellular protozoan parasite that can infect warm\u2010blooded animals including humans. New World monkeys, such as squirrel monkeys, are more susceptible to <jats:italic>T.\u00a0gondii<\/jats:italic> than Old World monkeys, often developing fatal disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, seven of thirteen dead squirrel monkeys at Seoul Grand Park were tested to find the cause of sudden death.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The main histopathological findings included interstitial pneumonia, necrotizing hepatitis, and splenitis. Periodic acid\u2010Schiff staining of liver, spleen, and lung revealed cyst structures consistent with bradyzoites. Amplification of the <jats:italic>B1<\/jats:italic> gene was detected in the liver or spleen of all monkeys. Additionally, a restriction fragment length polymorphism assay and phylogenetic analysis of the <jats:styled-content style=\"fixed-case\">GRA<\/jats:styled-content>6 amplicon revealed a consistent clustering with the type <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> strain of <jats:italic>T.\u00a0gondii<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study is the first report of <jats:italic>T.\u00a0gondii<\/jats:italic> infection of squirrel monkeys in Korea, and the first report of type <jats:styled-content style=\"fixed-case\">II <\/jats:styled-content><jats:italic>T.\u00a0gondii<\/jats:italic> based on <jats:styled-content style=\"fixed-case\">GRA<\/jats:styled-content>6 analysis in Korea.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12344","type":"journal-article","created":{"date-parts":[[2018,4,30]],"date-time":"2018-04-30T12:27:34Z","timestamp":1525091254000},"page":"238-246","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["An outbreak of toxoplasmosis in squirrel monkeys (<i>Saimiri sciureus<\/i>) in South Korea"],"prefix":"10.1111","volume":"47","author":[{"given":"Hanseul","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Laboratory Animal Medicine College of Veterinary Medicine Seoul National University  Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Yeon","family":"Eo","sequence":"additional","affiliation":[{"name":"Conservation and Health Center Seoul Zoo  Gwacheon Gyonggido 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