{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:56:18Z","timestamp":1740124578815,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T00:00:00Z","timestamp":1555891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100013221","name":"Razi vaccine and serum research institute","doi-asserted-by":"crossref","award":["2-18-18-88037"],"award-info":[{"award-number":["2-18-18-88037"]}],"id":[{"id":"10.13039\/501100013221","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Nowadays, several test methods with different useful values are available for diagnosis of the tuberculosis (TB) in non\u2010human primates (NHPs). Despite some limitations of tuberculin skin test (TST), it is still the most commonly used method for TB testing of NHPs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During this investigation, TST was performed upon three groups of experimentally tuberculin sensitized and one group of non\u2010sensitized vervet monkeys (<jats:italic>Chlorocebus pygerythrus<\/jats:italic>) by means of two types of old tuberculin (OT) and two types of purified protein derivative (PPD) tuberculin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The data obtained from this study revealed that PPD tuberculin prepared from both <jats:italic>Mycobacterium tuberculosis<\/jats:italic> and <jats:italic>Mycobacterium bovis<\/jats:italic> has more advantages over OT in tuberculin testing of the vervet monkeys. The potency of the PPD tuberculin prepared from <jats:italic>M\u00a0bovis<\/jats:italic> was estimated almost twice as much of the <jats:italic>M\u00a0tuberculosis<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intrapalpebral injection of 0.1\u00a0mL of a concentration of \u22651\u00a0mg\/mL of PPD tuberculin prepared from <jats:italic>M\u00a0bovis<\/jats:italic> is the preferred method for TST of vervet monkeys.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12413","type":"journal-article","created":{"date-parts":[[2019,4,23]],"date-time":"2019-04-23T06:11:20Z","timestamp":1555999880000},"page":"218-225","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of tuberculin skin test (TST) in vervet monkeys (<i>Chlorocebus pygerythrus<\/i>) using experimentally tuberculin sensitized animals"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8144-6842","authenticated-orcid":false,"given":"Mohammad Hassan","family":"Hablolvarid","sequence":"first","affiliation":[{"name":"Department of Pathology and Epidemiology, Razi Vaccine and Serum Research Institute Agricultural Research, Education and Extension Organization (AREEO) Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Eslampanah","sequence":"additional","affiliation":[{"name":"Department of Pathology and Epidemiology, Razi Vaccine and Serum Research Institute Agricultural Research, Education and Extension Organization (AREEO) Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nader","family":"Mosavari","sequence":"additional","affiliation":[{"name":"Bovine Tuberculosis Reference Laboratory, Razi Vaccine and Serum Research Institute Agricultural Research, Education and Extension Organization (AREEO) Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Baradaran\u2010Seyed","sequence":"additional","affiliation":[{"name":"Department of Pathology and Epidemiology, Razi Vaccine and Serum Research Institute Agricultural Research, Education and Extension Organization (AREEO) Karaj Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-71911-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","unstructured":"LinPL FlynnJLTuberculosis research using nonhuman primates. 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