{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T23:42:08Z","timestamp":1780962128810,"version":"3.54.1"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cholelithiasis is a digestive system disorder of multifactorial origin that occurs due to stones formed in the gallbladder. This study aimed at investigating by abdominal ultrasound examination the prevalence of cholelithiasis in lion tamarins kept under human care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty lion tamarins from five Brazilian zoos, including 17 golden lion tamarins and 13 golden\u2010headed lion tamarins, were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Considering all lion tamarins, the overall frequency of cholelithiasis was 53.3% (16\/30). There were no significant differences between species and sex. Cholelithiasis was predominant (75.0%) in lion tamarins older than 5\u2009years. Septate gallbladder was observed in 86.6% (26\/30) of the lion tamarins. Of these, 53.8% (14\/26) had gallstones. Biochemical analysis revealed a moderate positive correlation between gamma\u2010glutamyl transferase and the number of gallstones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Asymptomatic cholelithiasis is frequent in lion tamarins kept under human care. Therefore, systematic monitoring through ultrasound should be part of the preventive care of these animals.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12615","type":"journal-article","created":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T05:28:36Z","timestamp":1661578116000},"page":"17-23","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of cholelithiasis in lion tamarins (<i>Leontopithecus<\/i> spp.) kept under human care by using abdominal ultrasound"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8552-5126","authenticated-orcid":false,"given":"Daniel Angelo","family":"Felippi","sequence":"first","affiliation":[{"name":"Graduate Program in Wild Animals, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3650-8861","authenticated-orcid":false,"given":"Paolla Nicole","family":"Franco","sequence":"additional","affiliation":[{"name":"Graduate Program in Wild Animals, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6716-2288","authenticated-orcid":false,"given":"Shayra Peruch","family":"Bonatelli","sequence":"additional","affiliation":[{"name":"Graduate Program in Wild Animals, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2852-6288","authenticated-orcid":false,"given":"Jeana Pereira","family":"da Silva","sequence":"additional","affiliation":[{"name":"Graduate Program in Wild Animals, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5973-9430","authenticated-orcid":false,"given":"Victor Yunes","family":"Guimar\u00e3es","sequence":"additional","affiliation":[{"name":"Graduate Program in Wild Animals, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"},{"name":"Veterinary Clinical Laboratory, Veterinary Clinic Department, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9249-296X","authenticated-orcid":false,"given":"Maria Rosa Santos","family":"Breda","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Laboratory, Veterinary Clinic Department, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Pagani","sequence":"additional","affiliation":[{"name":"Hermann Weege Foundation (Pomerode Zoo)  Pomerode Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna","family":"dos Santos","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Animal Science University of S\u00e3o Paulo (USP)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3323-4199","authenticated-orcid":false,"given":"Regina Kiomi","family":"Takahira","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Laboratory, Veterinary Clinic Department, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University  Botucatu Brazil"},{"name":"Department of Veterinary Clinics, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9211-4093","authenticated-orcid":false,"given":"Sheila Canevese","family":"Rahal","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2238-5584","authenticated-orcid":false,"given":"Maria Jaqueline","family":"Mamprim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science S\u00e3o Paulo State University (Unesp)  Botucatu Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Taxonomy of the neotropical primates \u2013 database. 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