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Increased levels of stress in primates have been presented with increased levels of pruritus and alopecia appearance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A pruritic and alopecic disease was investigated in a group of tufted capuchin monkeys (<jats:italic>N<\/jats:italic>\u2009=\u200912), but due to ethical reasons, four random animals were further investigated by numerous diagnostic methods. The impact of food and enclosure enrichment was assessed and observed over a 2\u2010year period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Histopathology of four random tufted capuchin monkeys revealed lymphocytic perifolliculitis, with an appearance of a \u201cswarm of bees\u201d which was suggestive of alopecia areata. Etiological classification of pruritus excluded dermatological, systemic, and neurological causes, making it behavioral. Enclosure and food enrichment had a beneficial impact on pruritus (12\/12) and alopecia (10\/12).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings were suggestive of alopecia areata, while the pruritus was considered behavioral in origin. Alopecia and pruritus improved upon enclosure and food enrichment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmp.12645","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T11:08:05Z","timestamp":1682680085000},"page":"244-258","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and histopathological investigation of symmetrical alopecia with associated chronic pruritus in tufted capuchin monkeys (<i>Sapajus apella apella<\/i>)"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2367-5364","authenticated-orcid":false,"given":"Ana","family":"Petak","sequence":"first","affiliation":[{"name":"Clinic for Small Animals \u201cBuba\u201d  Zagreb Croatia"},{"name":"Faculty of Veterinary Medicine, University of Zagreb  Zagreb 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