{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T18:15:53Z","timestamp":1789064153672,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Owl monkeys (\n                      <jats:italic>Aotus<\/jats:italic>\n                      spp.) are a nocturnal nonhuman primate (NHP) native to central and South America that are used as infectious disease research models for human diseases, such as malaria and human immunodeficiency virus. Natural and infectious diseases may cause alterations in the hematology and serum biochemistry values, which necessitate the availability of reliable reference intervals for healthy animals.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this study, hematology and serum chemistry reference intervals for\n                      <jats:italic>Aotus nancymae<\/jats:italic>\n                      were calculated from 191 healthy animals (95 female, 96 male) and were generated based on age class (juvenile, adult, geriatric), sex (adults only), and across the entire sample.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Significant differences were observed in multiple parameters as a function of sex and age, some of which are inconsistent with existing data from\n                      <jats:italic>Aotus<\/jats:italic>\n                      spp. and other\n                      <jats:styled-content style=\"fixed-case\">NHPs.<\/jats:styled-content>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The availability of age and sex specific reference intervals will be a valuable resource for monitoring the clinical health and effects of research interventions in owl monkeys.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jmp.70092","type":"journal-article","created":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T05:34:18Z","timestamp":1782538458000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hematology and Serum Biochemistry Reference Intervals for Captive\u2010Born Owl Monkeys (\n                    <i>Aotus nancymae<\/i>\n                    ): Effects of Age and Sex"],"prefix":"10.1111","volume":"55","author":[{"given":"Sarah M.","family":"Kezar","sequence":"first","affiliation":[{"name":"Department of Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research The University of Texas MD Anderson Cancer Center  Bastrop Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9393-3528","authenticated-orcid":false,"given":"Sarah J.","family":"Neal","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research The University of Texas MD Anderson Cancer Center  Bastrop Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory K.","family":"Wilkerson","sequence":"additional","affiliation":[{"name":"Department of Comparative Medicine, Michale E. Keeling Center for Comparative Medicine and Research The University of Texas MD Anderson Cancer Center  Bastrop Texas USA"},{"name":"Department of Pathology and Laboratory Medicine University of North Carolina  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-409527-4.00017-1"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-031-13555-2_21"},{"key":"e_1_2_10_4_1","unstructured":"ITIS \u201cAotus nancymaiHershkovitz 1983 \u201d inIntegrated Taxonomic Information System (ITIS) On\u2010line Database accessed May 26 2026 https:\/\/www.itis.gov\/servlet\/SingleRpt\/SingleRpt?search_topic=TSN&search_value=1147534#null."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-026-70209-5"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1089\/vim.2014.0090"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.2092"},{"issue":"2","key":"e_1_2_10_8_1","first-page":"143","article-title":"Serum Chemistry of the Wild Caught Karyotype I Night Monkey (\n                     Aotus nancymai\n                  )","volume":"41","author":"Malaga C.","year":"1991","journal-title":"Laboratory Animal Science"},{"key":"e_1_2_10_9_1","unstructured":"C.Malaga R. E.Weller R. L.Buschbom andH. A.Ragan \u201cHematology of the Wild Caught Karyotype 1 Owl Monkey (Aotus nancymai) \u201d 1990."},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-072405-5.50010-X"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2010.00452.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.30802\/AALAS-JAALAS-21-000061"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajp.23589"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmp.12677"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41684-025-01547-y"},{"key":"e_1_2_10_16_1","unstructured":"S. M.Kezar \u201cHematology and Serum Biochemistry Data for 191Aotus nancymae \u201d 2026."},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12006"},{"key":"e_1_2_10_18_1","volume-title":"Exploratory Data Analysis","author":"Tukey J. 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