{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:50:34Z","timestamp":1792068634719,"version":"4.4.0"},"reference-count":55,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Medical Primatology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Owl monkeys are nonhuman primate species in the genus\n                      <jats:italic>Aotus<\/jats:italic>\n                      . The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys:\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>Aotus nancymai<\/jats:italic>\n                      <\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>A. vociferans<\/jats:italic>\n                      <\/jats:styled-content>\n                      ,\n                      <jats:styled-content style=\"fixed-case\">\n                        <jats:italic>A. azarae<\/jats:italic>\n                      <\/jats:styled-content>\n                      , and\n                      <jats:italic>\n                        <jats:styled-content style=\"fixed-case\">A. griseimembra<\/jats:styled-content>\n                        .\n                      <\/jats:italic>\n                      Disease of the hepatobiliary system has not been well characterized in\n                      <jats:italic>Aotus.<\/jats:italic>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Necropsy records from a 17\u2010year period were reviewed to characterize the gross and microscopic lesions of liver disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>316 adult owl monkeys were submitted for necropsy in the review period; 22 of 316 (6.96%) were diagnosed with hepatobiliary disease. Cardiac\u2010associated hepatopathy was the most common diagnosis (6\/22). Previously unreported conditions included cystic mucinous hyperplasia (1\/22), acute cholangiohepatitis (1\/22), idiopathic end\u2010stage hepatopathy (1\/22), cholangiocarcinoma (2\/22), and acute cholecystitis (4\/22). Vitamin E deficiency anemia (3\/22) and hemosiderosis (4\/22) have been reported in the genus, and these diagnoses were noted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The spectrum of hepatobiliary pathology in owl monkeys is broader than previous reports have suggested.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jmp.70114","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:52:39Z","timestamp":1789026759000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spontaneous Hepatobiliary Disease in a Breeding Colony of\n                    <scp>\n                      <i>Aotus<\/i>\n                      spp.\n                    <\/scp>"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8520-0279","authenticated-orcid":false,"given":"M. E.","family":"Hensel","sequence":"first","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research The University of Texas MD Anderson Cancer Center  Bastrop Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. W.","family":"Wilkerson","sequence":"additional","affiliation":[{"name":"Division of Comparative Medicine, School of Medicine The University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Yan","sequence":"additional","affiliation":[{"name":"Michale E. Keeling Center for Comparative Medicine and Research The University of Texas MD Anderson Cancer Center  Bastrop Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4113-7081","authenticated-orcid":false,"given":"C. L.","family":"Hodo","sequence":"additional","affiliation":[{"name":"Michale E. 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