{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T10:54:03Z","timestamp":1758970443545,"version":"3.40.5"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T00:00:00Z","timestamp":1552867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Midwife Womens Health"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Clinical studies conducted in the early to mid\u2010twentieth century, and recent self\u2010reports by some maternal placentophagy practitioners, suggest that human maternal placentophagy improves breast milk quality and quantity, although little research has evaluated this claim. Some placentophagy providers and advocates suggest that increased prolactin levels after placenta ingestion could account for the purported lactation benefits. The current study was conducted to evaluate these claims by comparing plasma prolactin levels of women consuming steamed, dehydrated, and encapsulated placenta with those of women consuming a placebo. Neonatal weight gain was also compared between the 2 groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A randomized, double\u2010blind, placebo\u2010controlled pilot trial was conducted in which postpartum women (N = 27) were given a supplement containing their dehydrated placenta (n = 12) or placebo (n = 15). Plasma prolactin concentrations were measured 4 times across late pregnancy and early postpartum, and neonatal weights were recorded 3 times over the first 3 weeks postpartum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The results showed no statistically significant (<jats:italic>P<\/jats:italic> &lt; .05) differences in either plasma prolactin levels or neonatal weight gain between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Maternal consumption of steamed, dehydrated, and encapsulated placenta postpartum does not appear to affect maternal postpartum prolactin or neonatal weight in the first 3 weeks postpartum. Further research is needed to investigate the possible effects of variation in placenta preparation methods or daily intake on human lactation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/jmwh.12955","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T23:49:06Z","timestamp":1553039346000},"page":"443-450","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Ingestion of Steamed and Dehydrated Placenta Capsules Does Not Affect Postpartum Plasma Prolactin Levels or Neonatal Weight Gain: Results from a Randomized, Double\u2010Bind, Placebo\u2010Controlled Pilot Study"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7937-0394","authenticated-orcid":false,"given":"Sharon M.","family":"Young","sequence":"first","affiliation":[{"name":"Nutrition and Reproduction Lab, Department of Anthropology University of Nevada, Las Vegas  Las Vegas Nevada"},{"name":"Office of Undergraduate Research University of Nevada, Las Vegas  Las Vegas Nevada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura K.","family":"Gryder","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Medicine University of Nevada, Las Vegas  Las Vegas Nevada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chad L.","family":"Cross","sequence":"additional","affiliation":[{"name":"Department of Environmental and Occupational Health University of Nevada, Las Vegas  Las Vegas Nevada"},{"name":"Department of Radiation Oncology, School of Medicine University of Nevada, Las Vegas  Las Vegas Nevada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Zava","sequence":"additional","affiliation":[{"name":"ZRT Laboratory  Beaverton Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wendy","family":"Norris","sequence":"additional","affiliation":[{"name":"ZRT Laboratory  Beaverton Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel C.","family":"Benyshek","sequence":"additional","affiliation":[{"name":"Nutrition and Reproduction Lab, Department of Anthropology University of Nevada, Las Vegas  Las Vegas Nevada"},{"name":"School of Medicine University of Nevada, Las Vegas  Las Vegas Nevada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,18]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2017.08.016"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wombi.2017.09.023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wombi.2017.11.004"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmwh.12549"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/03670244.2012.719356"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1891\/2158-0782.5.4.116"},{"issue":"1","key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0021-9258(18)86759-X","article-title":"The effect of the ingestion of desiccated placenta on the variations in the composition of human milk during the first eleven days after parturition","volume":"30","author":"Hammett FS","year":"1917","journal-title":"J Biol Chem"},{"key":"e_1_2_8_9_1","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0021-9258(18)86389-X","article-title":"The effect of the maternal ingestion of desiccated placenta upon the rate of growth of the breast\u2010fed infant","volume":"36","author":"Hammett FS.","year":"1918","journal-title":"J Biol Chem"},{"key":"e_1_2_8_10_1","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S0021-9258(18)86764-3","article-title":"Variations in the composition of human milk during the first eleven days after parturition","volume":"29","author":"Hammett FS","year":"1917","journal-title":"J Biol Chem"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1918.45.4.396"},{"issue":"6","key":"e_1_2_8_12_1","first-page":"617","article-title":"Placenta as a lactagagon","volume":"138","author":"Soykov\u00e1\u2010Pachnerov\u00e1 E","year":"1954","journal-title":"Gynaecologia"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/birt.12354"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.3.607"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.midw.2003.12.011"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2017.11.004"},{"volume-title":"Basic Medical Endocrinology","year":"2003","author":"Goodman HM.","key":"e_1_2_8_17_1"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0600273"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2018.05.006"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6625a4"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjom.2012.20.7.464"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jmwh.12309"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00737-015-0538-8"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogn.2015.10.008"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nwh.2016.08.005"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000128599"},{"volume-title":"Prolactin: Physiology and Clinical Significance","author":"Horrobin DF.","key":"e_1_2_8_27_1"}],"container-title":["Journal of Midwifery &amp; Women's Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjmwh.12955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jmwh.12955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jmwh.12955","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jmwh.12955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T03:10:34Z","timestamp":1694229034000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jmwh.12955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,18]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/jmwh.12955"],"URL":"https:\/\/doi.org\/10.1111\/jmwh.12955","archive":["Portico"],"relation":{},"ISSN":["1526-9523","1542-2011"],"issn-type":[{"type":"print","value":"1526-9523"},{"type":"electronic","value":"1542-2011"}],"subject":[],"published":{"date-parts":[[2019,3,18]]},"assertion":[{"value":"2018-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}