{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:24:13Z","timestamp":1777861453293,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T00:00:00Z","timestamp":1721606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Midwife Womens Health"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Although the development of postpartum granulation tissue (PPGT) is an expected phase of healing of perineal and vaginal lacerations, the persistence of this tissue can result in delayed wound healing, pain, bleeding, and discharge. There is a paucity of information on the efficacy of the treatments used for pathologic PPGT. The objective of this study was to describe characteristics associated with the development of PPGT and the treatment methods currently used for management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This was a retrospective cohort study of 140 patients diagnosed with PPGT within one year of birth from 2012 through 2022 within a single health care system. Patients were identified by\n                      <jats:italic>International Classification of Diseases<\/jats:italic>\n                      and Current Procedural Terminology codes. Demographics, birth characteristics, symptoms, and treatment information were obtained and assessed in frequencies and means. Treatments were compared with 95% CIs and\n                      <jats:italic>P<\/jats:italic>\n                      values. Time to resolution was assessed by the number of weeks and the number of visits.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>It was the first vaginal birth for 129 (92%) patients in the study cohort. The majority (84.3%) of patients presented with pain. Almost half of all patients (45%) were diagnosed after 6 weeks postpartum. 30.0% of patients were initially treated conservatively. 76.4% of patients were treated with silver nitrate, and 33.6% had an excisional procedure. Successful conservative management had the lowest average number of visits to resolution with 1.39 visits (95% CI, 1.15\u20101.69), followed by silver nitrate alone with 1.95 visits (95% CI, 1.73\u20102.19), and excision with or without silver nitrate with 2.40 visits (95% CI, 2.07\u20102.78). Conservative management was unsuccessful 45% of the time, requiring additional treatment with silver nitrate or excision. 30% of patients treated with silver nitrate or excision continued to report pain even after the resolution of granulation tissue upon examination.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PPGT is commonly associated with first vaginal births, often presents beyond 6 weeks postpartum, and frequently requires treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jmwh.13669","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T00:58:52Z","timestamp":1721696332000},"page":"104-110","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Presentation and Management of Postpartum Granulation Tissue: A Single\u2010Institution Retrospective Study"],"prefix":"10.1111","volume":"70","author":[{"given":"Bethany","family":"Kette","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology MedStar Washington Hospital Center  Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison","family":"Kumnick","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology MedStar Washington Hospital Center  Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6621-3947","authenticated-orcid":false,"given":"Serenity","family":"Budd","sequence":"additional","affiliation":[{"name":"MedStar Health Research Institute  Hyattsville Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8105-5868","authenticated-orcid":false,"given":"Neha","family":"Gaddam","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology MedStar Washington Hospital Center  Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Hazen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology MedStar Georgetown University Hospital  Washington District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2010.19.Sup2.47244"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.1999.8.10.26222"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14297"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192\u2010020\u201004405\u20102"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1967.tb97711.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0020\u20107292(98)00054\u2010x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0000000000001076"},{"issue":"12","key":"e_1_2_7_9_1","first-page":"1191","article-title":"Pulsed dye laser for the treatment of hypergranulation tissue with chronic ulcer in postsurgical defects","volume":"6","author":"Wang SQ","year":"2007","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12978"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.5070\/D38CN396S7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002223"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2147\/IMCRJ.S113182"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525\u20101470.2012.01724.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2014.03.017"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102230.1990.tb02152.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13829"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14836"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2021.30.Sup20.S8"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g6829"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPV.0b013e3181cc8702"},{"key":"e_1_2_7_22_1","unstructured":"CunninghamF LevenoKJ BloomSL et\u00a0al. eds.Williams Obstetrics.25th ed.McGraw\u2010Hill Education;2018. 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