{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:14:33Z","timestamp":1790727273217,"version":"4.1.0"},"reference-count":129,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["16H04671"],"award-info":[{"award-number":["16H04671"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["16K14578"],"award-info":[{"award-number":["16K14578"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17H05512"],"award-info":[{"award-number":["17H05512"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["17H05750"],"award-info":[{"award-number":["17H05750"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["26870282"],"award-info":[{"award-number":["26870282"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17K17215"],"award-info":[{"award-number":["17K17215"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17H01392"],"award-info":[{"award-number":["17H01392"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["17K18007"],"award-info":[{"award-number":["17K18007"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP16H06280"],"award-info":[{"award-number":["JP16H06280"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004906","name":"Fugaku Trust for Medicinal Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004906","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008883","name":"Nagoya City University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008883","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Neurochemistry"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Abstract<\/jats:title><jats:p>In the adult mammalian brain, neural stem cells (NSCs) reside in two neurogenic regions, the walls of the lateral ventricles, and the subgranular zone of the hippocampus, which generate new neurons for the olfactory bulb and dentate gyrus, respectively. These adult NSCs retain their self\u2010renewal ability and capacity to differentiate into neurons and glia as demonstrated by<jats:italic>in\u00a0vitro<\/jats:italic>studies. However, their contribution to tissue repair in disease and injury is limited, lending credence to the claim by prominent neuropathologist Ram\u00f3n y Cajal that \u2018once development was ended, the founts of growth and regeneration of the axons and dendrites dried up irrevocably\u2019. However, recent progress toward understanding the fundamental biology of adult NSCs and their role in pathological conditions has provided new insight into the potential therapeutic utility of endogenous NSCs. In this short review, we highlight two topics: the altered behavior of NSCs\u00a0after brain damage and the dysfunction of NSCs and\u00a0oligodendrocyte precursor cells, another type of undifferentiated cell in the adult brain, in mood affective disorders.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p><jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/jnc14557-fig-0003-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p><\/jats:sec>","DOI":"10.1111\/jnc.14557","type":"journal-article","created":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T14:33:08Z","timestamp":1532097188000},"page":"584-594","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Adult neurogenesis and its role in brain injury and psychiatric diseases"],"prefix":"10.1111","volume":"147","author":[{"given":"Yoshitaka","family":"Hayashi","sequence":"first","affiliation":[{"name":"Department of Integrative Physiology Shiga University of Medical Science Otsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Jinnou","sequence":"additional","affiliation":[{"name":"Department of Developmental and Regenerative Biology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"},{"name":"Department of Pediatrics and Neonatology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1984-5129","authenticated-orcid":false,"given":"Kazunobu","family":"Sawamoto","sequence":"additional","affiliation":[{"name":"Department of Developmental and Regenerative Biology Nagoya City University Graduate School of Medical Sciences Nagoya Japan"},{"name":"Division of Neural Development and Regeneration National Institute for Physiological Sciences Okazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6339-6802","authenticated-orcid":false,"given":"Seiji","family":"Hitoshi","sequence":"additional","affiliation":[{"name":"Department of Integrative Physiology Shiga University of Medical Science Otsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2014.0080"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-1136(200009)31:3<219::AID-GLIA30>3.0.CO;2-R"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/207953a0"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.02.051"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-03-00629.2002"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm747"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.129.18.4249"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.02.006"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2991-06.2007"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2008.198"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2009.75"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(01)00315-8"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0678-07.2007"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.02.033"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(98)00693-9"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)90524-Q"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2000.0751729.x"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.6.545"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/12.4.386"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020430"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000321607"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2014.04.027"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301275"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044-7431(03)00210-0"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2893.2007.00887.x"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-008-0189-x"},{"key":"e_1_2_13_28_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0022-3565(24)29244-2","article-title":"Regulation of adult neurogenesis by psychotrophic drugs and stress","volume":"299","author":"Duman R. S.","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.34"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.03.003"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4886(03)00209-7"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/3305"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2015.08.002"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.08.020"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.12.016"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201300287"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.01.003"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2017.01.005"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5457.1433"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(02)00060-X"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1580407"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.12-09-03642.1992"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055039"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2011.205"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2011.152"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033019"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2007-1032"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.975202"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.21455"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.12.6728"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.05.004"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0807059105"},{"key":"e_1_2_13_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-1591(02)00015-6"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.125.16.3167"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0603512103"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.11.005"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14002"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.07.007"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a018929"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.99"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4002110"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000236025.44089.e1"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2004.07.008"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.306"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600402"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2016.06.008"},{"key":"e_1_2_13_67_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.051508.135600"},{"key":"e_1_2_13_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2010.08.026"},{"key":"e_1_2_13_69_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.88609"},{"key":"e_1_2_13_70_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4273-11.2011"},{"key":"e_1_2_13_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr302"},{"key":"e_1_2_13_72_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4085-05.2006"},{"key":"e_1_2_13_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep46548"},{"key":"e_1_2_13_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2004.09.030"},{"key":"e_1_2_13_75_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a018820"},{"key":"e_1_2_13_76_1","first-page":"196","article-title":"Implications of adult hippocampal neurogenesis in antidepressant action","volume":"29","author":"Malberg J. E.","year":"2004","journal-title":"J. Psychiatry Neurosci."},{"key":"e_1_2_13_77_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1299-06.2006"},{"key":"e_1_2_13_78_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1117943109"},{"key":"e_1_2_13_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20155"},{"key":"e_1_2_13_80_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/915160"},{"key":"e_1_2_13_81_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhv141"},{"key":"e_1_2_13_82_1","doi-asserted-by":"publisher","DOI":"10.1159\/000301135"},{"key":"e_1_2_13_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.22087"},{"key":"e_1_2_13_84_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4323-06.2006"},{"key":"e_1_2_13_85_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.22.13290"},{"key":"e_1_2_13_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5532"},{"key":"e_1_2_13_87_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf7073"},{"key":"e_1_2_13_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.23896"},{"key":"e_1_2_13_89_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10393"},{"key":"e_1_2_13_90_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0237-07.2007"},{"key":"e_1_2_13_91_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017600"},{"key":"e_1_2_13_92_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhh060"},{"key":"e_1_2_13_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00041-4"},{"key":"e_1_2_13_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901450105"},{"key":"e_1_2_13_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001791"},{"key":"e_1_2_13_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600172"},{"key":"e_1_2_13_97_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2014.00219"},{"key":"e_1_2_13_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1211"},{"key":"e_1_2_13_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scr.2013.06.006"},{"key":"e_1_2_13_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10487"},{"key":"e_1_2_13_101_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1083328"},{"key":"e_1_2_13_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506008102"},{"key":"e_1_2_13_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2011.01.008"},{"key":"e_1_2_13_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3020"},{"key":"e_1_2_13_105_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4956-08.2009"},{"key":"e_1_2_13_106_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-12-05123.2003"},{"key":"e_1_2_13_107_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200317977"},{"key":"e_1_2_13_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960506)368:3<439::AID-CNE9>3.0.CO;2-6"},{"key":"e_1_2_13_109_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-004-0549-1"},{"key":"e_1_2_13_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.07.025"},{"key":"e_1_2_13_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2009.271"},{"key":"e_1_2_13_112_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2005-0281"},{"key":"e_1_2_13_113_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.488445"},{"key":"e_1_2_13_114_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4162-06.2006"},{"key":"e_1_2_13_115_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14289-4"},{"key":"e_1_2_13_116_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/13.6.580"},{"key":"e_1_2_13_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2009.12.006"},{"key":"e_1_2_13_118_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/174689"},{"key":"e_1_2_13_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2007.04.014"},{"key":"e_1_2_13_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22093"},{"key":"e_1_2_13_121_1","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamapsychiatry.102"},{"key":"e_1_2_13_122_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0149-06.2006"},{"key":"e_1_2_13_123_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600432"},{"key":"e_1_2_13_124_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21068"},{"key":"e_1_2_13_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21819"},{"key":"e_1_2_13_126_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000794"},{"key":"e_1_2_13_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.11.003"},{"key":"e_1_2_13_128_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600430"},{"key":"e_1_2_13_129_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2009.55"},{"key":"e_1_2_13_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2014.05.015"}],"container-title":["Journal of Neurochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjnc.14557","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jnc.14557","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jnc.14557","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/am-pdf\/10.1111%2Fjnc.14557","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jnc.14557","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,5]],"date-time":"2025-07-05T22:49:23Z","timestamp":1751755763000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jnc.14557"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":129,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,12]]}},"alternative-id":["10.1111\/jnc.14557"],"URL":"https:\/\/doi.org\/10.1111\/jnc.14557","archive":["Portico"],"relation":{},"ISSN":["0022-3042","1471-4159"],"issn-type":[{"value":"0022-3042","type":"print"},{"value":"1471-4159","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,29]]},"assertion":[{"value":"2018-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}