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However, recent psychiatric genetic studies have identified numerous risk genes and chromosome loci (copy number variation: CNV) which enable us to analyze at the single gene level and utilize system\u2010level approaches. In this review, we focus on ASD as a major neurodevelopmental disorder and review recent findings mainly from the bioinformatics of omics studies. Additionally, by comparing these data with other major psychiatric disorders, including schizophrenia (SCZ), we identify unique characteristics of both diseases from multiple enrichment, pathway, and protein\u2013protein interaction networks (PPIs) analyses using susceptible genes found in recent large\u2010scale genetic studies. These unified, systematic approaches highlight unique characteristics of both disorders from multiple aspects and demonstrate how convergent pathways can contribute to an understanding of the complex etiology of such neurodevelopmental and neuropsychiatric disorders.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>\n<jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/png\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/jnc15514-fig-0005-m.png\"><jats:alt-text>image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/jnc.15514","type":"journal-article","created":{"date-parts":[[2021,9,19]],"date-time":"2021-09-19T15:44:55Z","timestamp":1632066295000},"page":"647-659","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Molecular signatures from multi\u2010omics of autism spectrum disorders and schizophrenia"],"prefix":"10.1111","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0817-2643","authenticated-orcid":false,"given":"Jun","family":"Nomura","sequence":"first","affiliation":[{"name":"Department of Physiology and Cell Biology Kobe University School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Mardo","sequence":"additional","affiliation":[{"name":"Neuroscience concentration Department of Molecular and Cellular Biology Harvard University  Cambridge Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7153-266X","authenticated-orcid":false,"given":"Toru","family":"Takumi","sequence":"additional","affiliation":[{"name":"Department of Physiology and Cell Biology Kobe University School of Medicine  Kobe Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/2040-2392-4-36"},{"issue":"2","key":"e_1_2_11_3_1","article-title":"An automated method for finding molecular complexes in large protein interaction networks","volume":"4","author":"Bader G. 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