{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:44:51Z","timestamp":1792716291663,"version":"4.5.0"},"reference-count":179,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T00:00:00Z","timestamp":1401321600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:p>\n                    Oxytocin is a nonapeptide hormone that has a central role in the regulation of parturition and lactation. In this review, we address oxytocin receptor (\n                    <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>\n                    ) signalling and its role in the myometrium during pregnancy and in labour. The\n                    <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>\n                    belongs to the rhodopsin\u2010type (\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    lass 1) of the\n                    <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>\n                    \u2010protein coupled receptor superfamily and is regulated by changes in receptor expression, receptor desensitisation and local changes in oxytocin concentration. Receptor activation triggers a number of signalling events to stimulate contraction, primarily by elevating intracellular calcium (\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    a\n                    <jats:sup>2+<\/jats:sup>\n                    ). This includes inositol\u2010tris\u2010phosphate\u2010mediated store calcium release, store\u2010operated\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    a\n                    <jats:sup>2+<\/jats:sup>\n                    entry and voltage\u2010operated\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    a\n                    <jats:sup>2+<\/jats:sup>\n                    entry. We discuss each mechanism in turn and also discuss\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    a\n                    <jats:sup>2+<\/jats:sup>\n                    \u2010independent mechanisms such as\n                    <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                    a\n                    <jats:sup>2+<\/jats:sup>\n                    sensitisation. Because oxytocin induces contraction in the myometrium, both the activation and the inhibition of its receptor have long been targets in the management of dysfunctional and preterm labours, respectively. We discuss current and novel\n                    <jats:styled-content style=\"fixed-case\">OTR<\/jats:styled-content>\n                    agonists and antagonists and their use and potential benefit in obstetric practice. In this regard, we highlight three clinical scenarios: dysfunctional labour, postpartum haemorrhage and preterm birth.\n                  <\/jats:p>","DOI":"10.1111\/jne.12154","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T04:03:32Z","timestamp":1396497812000},"page":"356-369","source":"Crossref","is-referenced-by-count":263,"title":["Oxytocin: Its Mechanism of Action and Receptor Signalling in the Myometrium"],"prefix":"10.1111","volume":"26","author":[{"given":"S.","family":"Arrowsmith","sequence":"first","affiliation":[{"name":"Department of Cellular and Molecular Physiology Institute of Translational Medicine University of Liverpool Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Wray","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Physiology Institute of Translational Medicine University of Liverpool Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1906.sp001148"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj0040427"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0021-9258(18)49238-1","article-title":"The sequence of amino acids in oxytocin, with a proposal for the structure of oxytocin","volume":"205","author":"Vigneaud V","year":"1953","journal-title":"J Biol Chem"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2012.10.011"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6153132"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2004.05.001"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(91)90020-2"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2007.038125"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.2.629"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7254.2006.00393.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70580-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1113\/eph8602114"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01062278"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00374751"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1139\/y92-229"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(99)70573-9"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1113\/eph8602179"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2007.05.011"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2004.02.001"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.10.6440"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-005-1416-4"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2006.05.002"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.102.004119"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsgi.2005.12.007"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00018.2008"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2001.0707h.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceca.2004.10.002"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004240050761"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01117437"},{"key":"e_1_2_7_31_1","doi-asserted-by":"crossref","first-page":"10687","DOI":"10.1016\/S0021-9258(18)33877-8","article-title":"Oxytocin inhibition of (Ca2+\u00a0+\u00a0Mg2+)\u2010ATPase activity in rat myometrial plasma membranes","volume":"257","author":"Soloff MS","year":"1982","journal-title":"J Biol Chem"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01110.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020903"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gar078"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-09-0160"},{"key":"e_1_2_7_36_1","first-page":"201","article-title":"Pharmacomechanical coupling: the role of calcium, G\u2010proteins, kinases and phosphatases","volume":"134","author":"Somlyo AP","year":"1999","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.070615"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1999.276.2.E345"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(03)00925-6"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004240100668"},{"key":"e_1_2_7_41_1","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1677\/joe.0.1570405","article-title":"Hormonal regulation of connexin\u201043 in baboon corpora lutea","volume":"157","author":"Khan\u2010Dawood FS","year":"1998","journal-title":"J Endocrinol"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0146-0005(95)80046-8"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2012-1057"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.130.6.3547"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4731(90)90276-X"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.086785"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116169"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-6980(88)90149-9"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(05)80434-5"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod65.4.1150"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-0528.2003.00024.x"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1570343"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-53-4-730"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(83)90005-4"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-49-3-429"},{"key":"e_1_2_7_56_1","first-page":"425","article-title":"Plasma oxytocin during the first and second stages of spontaneous human labour","volume":"126","author":"Thornton S","year":"1992","journal-title":"Acta Endocrinol"},{"key":"e_1_2_7_57_1","first-page":"458","article-title":"Evaluation of enzyme inhibitors of pregnancy associated oxytocinase: application to the measurement of plasma immunoreactive oxytocin during human labour","volume":"114","author":"Burd JM","year":"1987","journal-title":"Acta Endocrinol"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-107-4-1117"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1100251"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1113\/eph8602186"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1071-5576(01)00105-8"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016348309155798"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.21.11699"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2826.1996.05266.x"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.136.1.154"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1540007"},{"key":"e_1_2_7_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(84)90677-X"},{"key":"e_1_2_7_68_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.137.2.780"},{"key":"e_1_2_7_69_1","first-page":"405","article-title":"Oxytocin and the timing of parturition. Influence of oxytocin receptor gene expression, oxytocin secretion, and oxytocin\u2010induced prostaglandin F2 alpha and E2 release","volume":"395","author":"Fuchs AR","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.164004"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117236"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021212"},{"key":"e_1_2_7_73_1","first-page":"395","article-title":"Gonadal steroid regulation of oxytocin and oxytocin receptor gene expression","volume":"395","author":"Zingg HH","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1677\/jme.0.0270175"},{"key":"e_1_2_7_75_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-0615"},{"key":"e_1_2_7_76_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1247190"},{"key":"e_1_2_7_77_1","first-page":"359","article-title":"A study of the motility of the intact uterus at term","volume":"73","author":"Ferguson J","year":"1941","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_7_78_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.137.8.3213"},{"key":"e_1_2_7_79_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.138.7.2763"},{"key":"e_1_2_7_80_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod59.5.1055"},{"key":"e_1_2_7_81_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0953-8194.2004.01164.x"},{"key":"e_1_2_7_82_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1660045"},{"key":"e_1_2_7_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(11)90768-6"},{"key":"e_1_2_7_84_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.6.8609"},{"key":"e_1_2_7_85_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1633616100"},{"key":"e_1_2_7_86_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20041363"},{"key":"e_1_2_7_87_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2000.01280.x"},{"key":"e_1_2_7_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(02)00475-3"},{"key":"e_1_2_7_89_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.098475"},{"key":"e_1_2_7_90_1","first-page":"311","article-title":"Conversion of the myometrial oxytocin receptor from low to high affinity state by cholesterol","volume":"395","author":"Fahrenholz F","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"e_1_2_7_91_1","first-page":"126","article-title":"Cholesterol depletion enhances both spontaneous and agonist\u2010evoked uterine smooth muscle contractions in a reversible manner","volume":"48","author":"Buxton IL","year":"2005","journal-title":"Proc West Pharmacol Soc"},{"key":"e_1_2_7_92_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00120.2004"},{"key":"e_1_2_7_93_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719107306229"},{"key":"e_1_2_7_94_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.140.12.5712"},{"key":"e_1_2_7_95_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod56.1.200"},{"key":"e_1_2_7_96_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0277"},{"key":"e_1_2_7_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00179-U"},{"key":"e_1_2_7_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2010.06.006"},{"key":"e_1_2_7_99_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063800"},{"key":"e_1_2_7_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.02.011"},{"key":"e_1_2_7_101_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036787"},{"key":"e_1_2_7_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)03093-6"},{"key":"e_1_2_7_103_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.5.625"},{"key":"e_1_2_7_104_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2005-0031"},{"key":"e_1_2_7_105_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.1200091"},{"key":"e_1_2_7_106_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108377"},{"key":"e_1_2_7_107_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105038"},{"key":"e_1_2_7_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.09.025"},{"key":"e_1_2_7_109_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc2337"},{"key":"e_1_2_7_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1999.tb08112.x"},{"key":"e_1_2_7_111_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02071318"},{"key":"e_1_2_7_112_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2002-0222"},{"key":"e_1_2_7_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1995.tb10880.x"},{"key":"e_1_2_7_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(96)70050-9"},{"key":"e_1_2_7_115_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod61.4.873"},{"key":"e_1_2_7_116_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-70-4-1142"},{"key":"e_1_2_7_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(94)90415-4"},{"key":"e_1_2_7_118_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016349609054663"},{"key":"e_1_2_7_119_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.5.594"},{"key":"e_1_2_7_120_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.10.3.423"},{"key":"e_1_2_7_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70027-4"},{"key":"e_1_2_7_122_1","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1001\/jama.1983.03340100051029","article-title":"Fasting and the precipitation of labor. The Yom Kippur effect","volume":"250","author":"Kaplan M","year":"1983","journal-title":"JAMA"},{"key":"e_1_2_7_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80162-6"},{"key":"e_1_2_7_124_1","first-page":"179","article-title":"Vasopressin concentration in cord blood: correlation with method of delivery and cord pH","volume":"60","author":"Parboosingh J","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_125_1","unstructured":"NICE 2008 National Institute for Health and Care Excellence London"},{"key":"e_1_2_7_126_1","first-page":"266","article-title":"Pelvic scoring for elective induction","volume":"24","author":"Bishop EH","year":"1964","journal-title":"Obstet Gynecol"},{"key":"e_1_2_7_127_1","first-page":"CD003246","article-title":"Intravenous oxytocin alone for cervical ripening and induction of labour","author":"Kelly AJ","year":"2001","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_128_1","unstructured":"NICE 2007 National Institute for Health and Care Excellence London"},{"key":"e_1_2_7_129_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.52.8.494"},{"key":"e_1_2_7_130_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1998.tb09362.x"},{"key":"e_1_2_7_131_1","first-page":"425","article-title":"Half\u2010life of oxytocin in blood of pregnant and non\u2010pregnant women","volume":"61","author":"Ryden G","year":"1969","journal-title":"Acta Endocrinol"},{"key":"e_1_2_7_132_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00634710"},{"key":"e_1_2_7_133_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-58-2-274"},{"key":"e_1_2_7_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.06.010"},{"key":"e_1_2_7_135_1","first-page":"CD007123","article-title":"Oxytocin versus no treatment or delayed treatment for slow progress in the first stage of spontaneous labour","volume":"6","author":"Bugg GJ","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_136_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000293094","article-title":"Oxytocin pharmacodynamics: effect of long infusions on uterine activity","volume":"31","author":"Crall HD","year":"1991","journal-title":"Gynecol Obstet Invest"},{"key":"e_1_2_7_137_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2011-000514"},{"key":"e_1_2_7_138_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020136"},{"key":"e_1_2_7_139_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1994.tb13008.x"},{"key":"e_1_2_7_140_1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/00016348009156934","article-title":"A comparative study of uterine activity and fetal heart rate pattern in labor induced with oral prostaglandin E2 or oxytocin","volume":"92","author":"Bremme K","year":"1980","journal-title":"Acta Obstet Gynecol Scand Suppl"},{"key":"e_1_2_7_141_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.1993.tb02382.x"},{"key":"e_1_2_7_142_1","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/S1701-2163(16)30628-4","article-title":"Fetal health surveillance in labour","volume":"24","author":"Liston R","year":"2002","journal-title":"J Obstet Gynaecol Can"},{"key":"e_1_2_7_143_1","first-page":"259","article-title":"Investigation of the oxytocin receptor at the molecular level","volume":"395","author":"Kimura T","year":"1995","journal-title":"Adv Exp Med Biol"},{"key":"e_1_2_7_144_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000118306.82556.43"},{"key":"e_1_2_7_145_1","first-page":"21","article-title":"A randomized trial of pulsatile vs continuous oxytocin infusion for labor induction","volume":"27","author":"Salamalekis E","year":"2000","journal-title":"Clin Exp Obstet Gynecol"},{"key":"e_1_2_7_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.11.001"},{"key":"e_1_2_7_147_1","first-page":"364","article-title":"A trial of pulsatile versus continuous oxytocin administration for the induction of labor","volume":"15","author":"Reid GJ","year":"1995","journal-title":"J Perinatol"},{"key":"e_1_2_7_148_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1988.tb06475.x"},{"key":"e_1_2_7_149_1","first-page":"CD000201","article-title":"Prophylactic ergometrine\u2010oxytocin versus oxytocin for the third stage of labour","author":"McDonald S","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.06.018"},{"key":"e_1_2_7_151_1","first-page":"CD005457","article-title":"Oxytocin agonists for preventing postpartum haemorrhage","author":"Su LL","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_152_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.2553.1609"},{"key":"e_1_2_7_153_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1969.tb05852.x"},{"key":"e_1_2_7_154_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2013.072884"},{"key":"e_1_2_7_155_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1250317"},{"key":"e_1_2_7_156_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1311183110"},{"key":"e_1_2_7_157_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719109352687"},{"key":"e_1_2_7_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2012.06.020"},{"key":"e_1_2_7_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogrm.2010.05.001"},{"key":"e_1_2_7_160_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/941057"},{"key":"e_1_2_7_161_1","doi-asserted-by":"publisher","DOI":"10.1097\/OGX.0b013e31816ff75b"},{"key":"e_1_2_7_162_1","first-page":"Ra268","article-title":"Oxytocin antagonists for tocolysis in preterm labour \u2013 a systematic review","volume":"8","author":"Coomarasamy A","year":"2002","journal-title":"Med Sci Monit"},{"key":"e_1_2_7_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2005.06.005"},{"key":"e_1_2_7_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.12.010"},{"key":"e_1_2_7_165_1","first-page":"CD004452","article-title":"Oxytocin receptor antagonists for inhibiting preterm labour","author":"Papatsonis D","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_166_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e6226"},{"key":"e_1_2_7_167_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2003.02540.x"},{"key":"e_1_2_7_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsgi.2004.02.008"},{"key":"e_1_2_7_169_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2120"},{"key":"e_1_2_7_170_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.106.053637"},{"key":"e_1_2_7_171_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.01.015"},{"key":"e_1_2_7_172_1","unstructured":"ClinicalTrials.gov. A Randomised Placebo\u2010controlled Double\u2010blind Parallel Groups Multinational Multicentre Trial Assessing the Effect of Barusiban Administered Subcutaneously on the Day of Transfer on Implantation and Pregnancy Rates in IVF\/ICSI Patients.2012."},{"key":"e_1_2_7_173_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590400021144"},{"key":"e_1_2_7_174_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb13302.x"},{"key":"e_1_2_7_175_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2012.02303.x"},{"key":"e_1_2_7_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2007.05.009"},{"key":"e_1_2_7_177_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.103.061200"},{"key":"e_1_2_7_178_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050022"},{"key":"e_1_2_7_179_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00057.2007"},{"key":"e_1_2_7_180_1","doi-asserted-by":"crossref","first-page":"S155","DOI":"10.1016\/j.ajog.2012.10.515","article-title":"A multicenter, randomized, double\u2010blind, placebo controlled phase 2 trial of retosiban, a selective oxytocin receptor antagonist, for the management of preterm labor","volume":"208","author":"Snidow J","year":"2013","journal-title":"Am J Obstet Gynecol"}],"container-title":["Journal of Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjne.12154","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjne.12154","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.12154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T15:24:50Z","timestamp":1696260290000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.12154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,29]]},"references-count":179,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/jne.12154"],"URL":"https:\/\/doi.org\/10.1111\/jne.12154","archive":["Portico"],"relation":{},"ISSN":["0953-8194","1365-2826"],"issn-type":[{"value":"0953-8194","type":"print"},{"value":"1365-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,29]]}}}