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The present study aimed to test this hypothesis by administering the Balloon Analogue Risk Task (<jats:styled-content style=\"fixed-case\">BART<\/jats:styled-content>) to 25 women with <jats:styled-content style=\"fixed-case\">BN<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">BED<\/jats:styled-content> and 27 healthy comparison women without a history of an eating disorder. Furthermore, we tested the effect of a divided dose of 64\u00a0<jats:styled-content style=\"fixed-case\">IU<\/jats:styled-content> of oxytocin on risk\u2010taking behaviour in the <jats:styled-content style=\"fixed-case\">BART<\/jats:styled-content>. Contrary to our hypothesis, women with <jats:styled-content style=\"fixed-case\">BN<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">BED<\/jats:styled-content> did not exhibit baseline differences in performance on the <jats:styled-content style=\"fixed-case\">BART<\/jats:styled-content> in the placebo condition (<jats:italic>t\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1.42, <jats:italic>df\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>50, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.161, <jats:italic>d\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.39). Oxytocin did not have a main effect on performance in the <jats:styled-content style=\"fixed-case\">BART<\/jats:styled-content> (<jats:italic>F\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.01, <jats:italic>df\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.907, \u03b7<jats:sup>2<\/jats:sup><jats:sub>partial<\/jats:sub>\u00a0&lt;\u00a00.001); however, there was an interaction, such that participants in the <jats:styled-content style=\"fixed-case\">BN<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">BED<\/jats:styled-content> participant group, compared to the healthy comparison group, demonstrated safer behaviour on the <jats:styled-content style=\"fixed-case\">BART<\/jats:styled-content> in the oxytocin condition, but not in the placebo condition (<jats:italic>F\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>4.29, <jats:italic>df\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1, <jats:italic>P\u00a0<\/jats:italic>=\u00a00.044, \u03b7<jats:sup>2<\/jats:sup><jats:sub>partial<\/jats:sub><jats:italic>\u00a0<\/jats:italic>=\u00a00.082). These findings cast doubt on the common assumption that individuals with <jats:styled-content style=\"fixed-case\">BN<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BED<\/jats:styled-content> exhibit greater risk\u2010taking behaviour in all domains and add to the evidence that oxytocin plays a functional role in modulating behaviours that entail trade\u2010offs between reward approach and risk in humans. We recommend that future dose\u2010response studies investigate the effect of oxytocin on reward approach behaviour further in women with recurrent binge eating behaviour, as well as the clinical significance of this effect.<\/jats:p>","DOI":"10.1111\/jne.12771","type":"journal-article","created":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T11:33:56Z","timestamp":1562585636000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The influence of oxytocin on risk\u2010taking in the balloon analogue risk task among women with bulimia nervosa and binge eating disorder"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0216-7432","authenticated-orcid":false,"given":"Monica","family":"Leslie","sequence":"first","affiliation":[{"name":"King's College London (KCL) Institute of Psychiatry, Psychology and Neuroscience (IoPPN) London 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