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To assess social behaviour and socio\u2010cognitive abilities in this patient group, we tested 13 patients and 23 healthy controls on self\u2010report questionnaires and an eye\u2010tracking paradigm including fast facial emotion recognition. Additionally, saliva oxytocin levels acquired before and after a physical stress induction were available from a previous study, representing the reactivity of the oxytocin system. The data revealed three major results. First, patients with an oxytocin\u2010release\u2010deficit scored higher on self\u2010reported autistic traits and reduced levels of hedonia for social encounters, although they showed no impairments in attributing mental states. Second, patients showed more difficulties in the fast emotion recognition task. Third, although automatic gaze behaviour during emotion recognition did not differ between groups, gaze behaviour was related to the reactivity of the oxytocin system across all participants. Taken together, these findings demonstrate the importance of investigating the reactivity of the oxytocin system and its relationship with social cognition. Our findings suggest that reduced emotional processing abilities may represent a pathological feature in a group of craniopharyngioma patients, indicating that this patient group might benefit from specific treatments within the social domain.<\/jats:p>","DOI":"10.1111\/jne.12842","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T21:40:33Z","timestamp":1583790033000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Oxytocin release deficit and social cognition in craniopharyngioma patients"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5283-2317","authenticated-orcid":false,"given":"Marie\u2010Luise","family":"Brandi","sequence":"first","affiliation":[{"name":"Independent Max Planck Research Group for Social Neuroscience Max Planck Institute of Psychiatry Munich 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