{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:38:42Z","timestamp":1791488322228,"version":"4.3.4"},"reference-count":178,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Prolactin is named after its vital role of promoting milk production during lactation, although it has been implicated in multiple functions within the body, including metabolism and energy homeostasis. Prolactin has been hypothesised to play a key role in driving many of the adaptations of the maternal body to allow the mother to meet the physiological demands of both pregnancy and lactation, including the high energetic demands of the growing foetus followed by milk production to support the offspring after birth. Prolactin receptors are found in many tissues involved in metabolism and food intake, such as the pancreas, liver, hypothalamus, small intestine and adipose tissue. We review the literature examining the effects of prolactin in these various tissues and how they relate to changes in function in physiological states of high prolactin, such as pregnancy and lactation, and in pathological states of hyperprolactinaemia in the adult. In many cases, whether prolactin promotes healthy metabolism or leads to dysregulation of metabolic functions is highly dependent on the situation. Overall, although prolactin may not play a major role in regulating metabolism and body weight outside of pregnancy and lactation, it definitely has the ability to contribute to metabolic function.<\/jats:p>","DOI":"10.1111\/jne.12888","type":"journal-article","created":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T18:18:23Z","timestamp":1593541103000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["Metabolic functions of prolactin: Physiological and pathological aspects"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5088-2377","authenticated-orcid":false,"given":"Felicitas","family":"Lopez\u2010Vicchi","sequence":"first","affiliation":[{"name":"Instituto de Biologia y Medicina Experimental Consejo Nacional de Investigaciones Cientificas y Tecnicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"De Winne","sequence":"additional","affiliation":[{"name":"Instituto de Biologia y Medicina Experimental Consejo Nacional de Investigaciones Cientificas y Tecnicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1537-5468","authenticated-orcid":false,"given":"Belen","family":"Brie","sequence":"additional","affiliation":[{"name":"Instituto de Biologia y Medicina Experimental Consejo Nacional de Investigaciones Cientificas y Tecnicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9146-7647","authenticated-orcid":false,"given":"Eleonora","family":"Sorianello","sequence":"additional","affiliation":[{"name":"Instituto de Biologia y Medicina Experimental Consejo Nacional de Investigaciones Cientificas y Tecnicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3578-6763","authenticated-orcid":false,"given":"Sharon R.","family":"Ladyman","sequence":"additional","affiliation":[{"name":"Centre for Neuroendocrinology Department of Anatomy School of Biomedical Sciences University of Otago Dunedin New Zealand"},{"name":"Maurice Wilkins Centre Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5641-3109","authenticated-orcid":false,"given":"Damasia","family":"Becu\u2010Villalobos","sequence":"additional","affiliation":[{"name":"Instituto de Biologia y Medicina Experimental Consejo Nacional de Investigaciones Cientificas y Tecnicas Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(01)33012-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.146316"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-979040"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-1208.121400"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2019.110679"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2019-00234"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2000.80.4.1523"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2011-1040"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.089185"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22208"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208960"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-016-1254-5"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22775"},{"key":"e_1_2_8_15_1","first-page":"R276","article-title":"Prolactin stimulates food intake in a dose\u2010dependent manner","volume":"256","author":"Gerardo\u2010Gettens T","year":"1989","journal-title":"Am J Physiol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(86)90226-1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(93)90057-M"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1120215"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(96)00075-6"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-100-1-182"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/hbeh.1998.1495"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-3182(84)72932-X"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1530\/acta.0.1250392"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.0.1470077"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2005.18.9.921"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1998.00403.x"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-032184"},{"key":"e_1_2_8_28_1","first-page":"254","article-title":"Increased prevalence of high Body Mass Index in patients presenting with pituitary tumours: severe obesity in patients with macroprolactinoma","volume":"136","author":"Schmid C","year":"2006","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-008-0097-3"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345636"},{"key":"e_1_2_8_31_1","first-page":"2030","article-title":"Nutritional and metabolic assessment in overweight patients with and without hyperprolactinemia caused by prolactinoma","volume":"32","author":"Breyer Freitas B","year":"2015","journal-title":"Nutr Hosp"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12183"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.150"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3109\/07435800.2015.1135444"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012879"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-010-0277-9"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13098-015-0094-4"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2009.10.010"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00327"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-013-9931-0"},{"key":"e_1_2_8_41_1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/BF00273860","article-title":"Severe hyperprolactinaemia is associated with decreased insulin binding in vitro and insulin resistance in vivo","volume":"28","author":"Schernthaner G","year":"1985","journal-title":"Diabetologia"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-009-0183-1"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03347025"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2006.02.005"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/cen.12204"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-51-2-242"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2006.02469.x"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2014.07.004"},{"issue":"27","key":"e_1_2_8_49_1","first-page":"15","article-title":"Hyperglycemia and antipsychotic medications","volume":"62","author":"Haupt DW","year":"2001","journal-title":"J Clin Psychiatry"},{"issue":"1","key":"e_1_2_8_50_1","first-page":"32","article-title":"Prolactin\u2010related and metabolic adverse effects of atypical antipsychotic agents","volume":"69","author":"Henderson DC","year":"2008","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_8_51_1","first-page":"176","article-title":"Effects of placental lactogen and progesterone on insulin stimulated glucose metabolism in rat muscles in vitro","volume":"15","author":"Leturque A","year":"1989","journal-title":"Diabete Metab"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.4.337"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2015.07.022"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-6-11"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0744"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-0487"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1291182"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.141.10.3564"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-1-12"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.11.2.167"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.23.6926"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2015-1232"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/12506"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125626"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81865-6"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.8.10.1298"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5335.135"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.25.15043"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/1082"},{"key":"e_1_2_8_70_1","first-page":"R701","article-title":"Prolactin stimulates food intake in the absence of ovarian progesterone","volume":"256","author":"Gerardo\u2010Gettens T","year":"1989","journal-title":"Am J Physiol"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2007.04.015"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-0442"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(96)00227-2"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)02344-1"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(89)90213-8"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1471-16.2016"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2005.01374.x"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12634"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2003-1255"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12474"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7624778"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215693"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7624777"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7624776"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2010.08.002"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-12-0112"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0338"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2007-1018"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12702"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2826.2010.02017.x"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.11.050"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2018-01065"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1707"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2019.107911"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/0031-9384(71)90050-3"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201902357R"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-021137"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(02)00165-9"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1159\/000093667"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1530\/JOE-15-0213"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2013.09.023"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.03.168"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.142.2.7979"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.14.2.307"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1224181"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-1172"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-12114-7_1"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00200.2016"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2020.01.004"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1023\/B:PITU.0000004800.57449.67"},{"key":"e_1_2_8_111_1","first-page":"56","article-title":"Prolactin promotes adipose tissue fitness and insulin sensitivity in obese males","volume":"158","author":"Ruiz\u2010Herrera X","year":"2017","journal-title":"Endocrinology"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201409063"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-204958"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001535"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2015.00150"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201701154R"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0790191"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041400117"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6823-13-12"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-013-0493-7"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-1893"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-018-4733-9"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-019-02170-x"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0209-139"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2010.08.017"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1089\/gtmb.2013.0009"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12716"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.133.3.8365359"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.2337\/db15-1527"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-1003"},{"key":"e_1_2_8_131_1","first-page":"G807","article-title":"Visualization of gene expression of short and long forms of prolactin receptor in rat digestive tissues","volume":"266","author":"Ouhtit A","year":"1994","journal-title":"Am J Physiol"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.136.9.7649117"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0201"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-110-2-600"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-121-4-1447"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2006-1219"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1640277"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00636.2012"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-019-0194-6"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1159\/000336501"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.1215"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-014-3336-3"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2019-00243"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1530\/EC-17-0171"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.12634"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2014-1714"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1530\/JME-19-0205"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-019-00652-0"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2018.03.048"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.01.035"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1404267111"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-1479"},{"key":"e_1_2_8_153_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0556-1"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2016.00168"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30626"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158817"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00003.2018"},{"key":"e_1_2_8_158_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00282.2013"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-948310"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.2337\/db13-0182"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.116.074658"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200443150-00002"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00420-06"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.08.030"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.130.5.1572300"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00142.2007"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/78.6.1178"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN19750005"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026332304435"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-74-5-714"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.22.7.558"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01922975"},{"key":"e_1_2_8_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2015.11.038"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1139\/y98-016"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1139\/cjpp-79-5-430"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2004.06.017"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-4-1-44"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-98-6-1370"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1708025114"}],"container-title":["Journal of Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fjne.12888","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.12888","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jne.12888","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.12888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T19:13:44Z","timestamp":1693854824000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.12888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,24]]},"references-count":178,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1111\/jne.12888"],"URL":"https:\/\/doi.org\/10.1111\/jne.12888","archive":["Portico"],"relation":{},"ISSN":["0953-8194","1365-2826"],"issn-type":[{"value":"0953-8194","type":"print"},{"value":"1365-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,24]]},"assertion":[{"value":"2020-02-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-23","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-07-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e12888"}}