{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:51:44Z","timestamp":1772160704534,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Patients with small intestine neuroendocrine tumours (SINETs) face various disease\u2010related symptoms that can affect their social functioning and quality of life. The present study aimed to explore the social consequences of disease\u2010related symptoms in patients with a metastatic SINET and to develop a theory on how these patients experience their disease. Patients were eligible when they were diagnosed with a metastatic SINET between 2009 and 2016 and were younger than 60\u00a0years of age during diagnosis, and had a good functional performance status. Semi\u2010structured interviews were conducted between January and June 2018. Data were transcribed and analysed independently by two researchers using grounded theory. Data saturation was reached at 10 interviews and, in total, 12 patients participated. A core component that arose from the interviews was resilience in the face of social consequences of having a metastatic SINET. Prominent physical symptoms were fatigue, diarrhoea and flushes. All of these symptoms were associated with limitations to function in work\u2010related and social activities, as well as feelings of embarrassment and shame. Adaptive strategies, such as careful planning, or focusing on the perspective to live well with a neuroendocrine tumour, helped patients to experience the consequences as less burdensome. Other helpful factors that were identified constituted social support, engaging in meaningful activities and financial stability. Patients with a metastatic SINET experienced social consequences of disease\u2010related symptoms in daily life, although they were able to attenuate the burden of these consequences by using adaptive problem\u2010based, emotion\u2010based and meaning\u2010based coping strategies. Clinicians could explore the perceived consequences and educate patients about adaptive strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/jne.12956","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T03:30:57Z","timestamp":1616038257000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Coping with social consequences of disease\u2010related symptoms in patients with a metastatic small intestinal neuroendocrine tumour: A qualitative study"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4099-2385","authenticated-orcid":false,"given":"Froukje E.","family":"de Vries","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Centre for Quality of Life Netherlands Cancer Institute Amsterdam The 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Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annelies H.","family":"Boekhout","sequence":"additional","affiliation":[{"name":"Department of Psychosocial Research and Epidemiology, Netherlands Cancer Institute Amsterdam The 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