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This systemic review will summarize the clinical, pathological features and optimal diagnosis and management of different types of nasopharyngeal NENs (NP NENs). In\u2010addition, we herein report an EBV negative TP53\u2010mutated\/ Rb\u2010wild type nasopharyngeal neuroendocrine carcinoma (NEC) in a young man in which touch preparation cytology studies were integral to establishing a definitive diagnosis. To our knowledge, only very few cases of primary neuroendocrine carcinoma of the nasopharynx have been reported in the literature and the reports of these cases have not included detailed description of different types and how to optimally diagnose and manage them. In this abstract, we also highlighted the evidence about the safety of using growth factors in patients with sickle cell anemia who are receiving cytotoxic chemotherapy.<\/jats:p>","DOI":"10.1111\/jne.13005","type":"journal-article","created":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T00:30:56Z","timestamp":1623976256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Nasopharyngeal neuroendocrine neoplasms: Systematic review of the literature and case presentation"],"prefix":"10.1111","volume":"33","author":[{"given":"Jain","family":"Prantesh","sequence":"first","affiliation":[{"name":"Department of Medicine Division of Hematology and Medical Oncology Seidman Cancer Center University Hospitals Case Western Reserve University Cleveland OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Dorth","sequence":"additional","affiliation":[{"name":"Department of Radiation 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