{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T03:12:26Z","timestamp":1784257946374,"version":"3.55.0"},"reference-count":201,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T00:00:00Z","timestamp":1634169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["P30 GM122733"],"award-info":[{"award-number":["P30 GM122733"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["R00 DA039791"],"award-info":[{"award-number":["R00 DA039791"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000009","name":"Foundation for the National Institutes of Health","doi-asserted-by":"publisher","award":["R01 DA052851"],"award-info":[{"award-number":["R01 DA052851"]}],"id":[{"id":"10.13039\/100000009","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Forty years into the HIV pandemic, approximately 50% of infected individuals still suffer from a constellation of neurological disorders collectively known as \u2018neuroHIV.\u2019 Although combination antiretroviral therapy (cART) has been a tremendous success, in its present form, it cannot eradicate HIV. Reservoirs of virus reside within the central nervous system, serving as sources of HIV virotoxins that damage mitochondria and promote neurotoxicity. Although understudied, there is evidence that HIV or the HIV regulatory protein, trans\u2010activator of transcription (Tat), can dysregulate neurosteroid formation potentially contributing to endocrine dysfunction. People living with HIV commonly suffer from endocrine disorders, including hypercortisolemia accompanied by paradoxical adrenal insufficiency upon stress. Age\u2010related comorbidities often onset sooner and with greater magnitude among people living with HIV and are commonly accompanied by hypogonadism. In the post\u2010cART era, these derangements of the hypothalamic\u2010pituitary\u2010adrenal and \u2010gonadal axes are secondary (i.e., relegated to the brain) and indicative of neuroendocrine dysfunction. We review the clinical and preclinical evidence for neuroendocrine dysfunction in HIV, the capacity for hormone therapeutics to play an ameliorative role and the future steroid\u2010based therapeutics that may have efficacy as novel adjunctives to cART.<\/jats:p>","DOI":"10.1111\/jne.13047","type":"journal-article","created":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T12:36:22Z","timestamp":1633350982000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Allopregnanolone and neuroHIV: Potential benefits of neuroendocrine modulation in the era of antiretroviral therapy"],"prefix":"10.1111","volume":"34","author":[{"given":"Mohammed F.","family":"Salahuddin","sequence":"first","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa N.","family":"Qrareya","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fakhri","family":"Mahdi","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emaya","family":"Moss","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas S.","family":"Akins","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"},{"name":"Research Institute of Pharmaceutical Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoang V.","family":"Le","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"},{"name":"Research Institute of Pharmaceutical Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5628-1134","authenticated-orcid":false,"given":"Jason J.","family":"Paris","sequence":"additional","affiliation":[{"name":"Department of BioMolecular Sciences School of Pharmacy University of Mississippi  University MS USA"},{"name":"Research Institute of Pharmaceutical Sciences School of Pharmacy University of Mississippi  University MS USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,14]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Preliminary UNAIDS 2021 Epidemiological Estimates","author":"Global HIV and AIDS Statistics\u2010Fact Sheet"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-015-0302-7"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2016.53"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.1999.tb01394.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2014.02.008"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2019.00362"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612822666160726113001"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2019.134475"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.04.030"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2055-6640(20)30275-2"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2017.04.015"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2040"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401623"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/13550280009013158"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199607000-00007"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002076"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00285"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002268"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1308673110"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-014-9524-6"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450116666150531162212"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611699104"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12724"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.3.1475-1480.1996"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5351-13.2014"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-48777-y"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.3390\/v12040471"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-021-03785-y"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-012-9353-4"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.irn.2019.04.003"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00993-18"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003916"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2011.12.019"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-016-0447-2"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0547-20.2021"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2018.04.046"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2018.04.018"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0226-17.2017"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2015.05.021"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2016.01.014"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.593188"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2017.04.002"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-013-3385-1"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2014.04.001"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.01.007"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2019.104649"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21218212"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/v13050813"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.663373"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/PR9.0000000000000654"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr900926n"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2017.11.006"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1618"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570162X13666150311163733"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2011.05.006"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2014.07.014"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2015.39"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.01.020"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-53466-x"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744806919868380"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20051196"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108399"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2016.00102"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-007-9078-y"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2019.34.2.95"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2009.0065"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.05.027"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062069"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2006.22.350"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2013.03.002"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2007.0108"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.1997.13.1235"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1086\/513434"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2013.05.019"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191916"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.20214"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.20793"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-6-40"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2001.00511.x"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2004.03.006"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2020.100211"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-021-01266-1"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.23291"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-34539-9"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-07570-5"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-215079"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa104"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2014.09.001"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2013.09.004"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3874-16.2017"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-013-9244-x"},{"key":"e_1_2_10_93_1","first-page":"17\u20100104","article-title":"Hypogonadotropic hypogonadism in human immunodeficiency virus\u2010infected men: uncommonly low testosterone levels","volume":"2017","author":"Gomes AC","year":"2017","journal-title":"Endocrinol Diabetes Metab Case Rep"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199106000-00013"},{"issue":"3","key":"e_1_2_10_95_1","first-page":"428","article-title":"Adrenal insufficiency In Pakistani HIV infected patients","volume":"29","author":"Afreen B","year":"2017","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecl.2014.06.002"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1258\/0956462011924434"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200206000-00018"},{"issue":"9","key":"e_1_2_10_99_1","first-page":"1768","article-title":"Prevalence of adrenal insufficiency in critically ill patients with AIDS","volume":"90","author":"Prasanthai V","year":"2007","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_43_16"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.16.3.18640"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-019-1256-2"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0174613"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2013.861574"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-016-1451-5"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.21.1.55"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.81.2.791"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(97)00015-2"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-70-3-572"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169827"},{"issue":"5","key":"e_1_2_10_111_1","first-page":"220","article-title":"Thyroid and adrenal function in HIV\u2010infected outpatients","volume":"2","author":"Sch\u00fcrmeyer TH","year":"1997","journal-title":"Eur J Med Res"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.74.3.608"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.121455098"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2018.06.013"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570162052772988"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M005197200"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1321.013"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.189.1.51"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1996.0664"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.2000.7502"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(01)00351-4"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.04984.x"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.10.5934"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.140.9.6986"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003840100331"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2002.122465"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.1.33"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2006.0071"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(88)90144-1"},{"issue":"5","key":"e_1_2_10_130_1","first-page":"1332","article-title":"Body composition and endocrine function in women with acquired immunodeficiency syndrome wasting","volume":"82","author":"Grinspoon S","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_10_131_1","doi-asserted-by":"publisher","DOI":"10.1086\/317457"},{"key":"e_1_2_10_132_1","doi-asserted-by":"publisher","DOI":"10.1177\/135965350701200215"},{"key":"e_1_2_10_133_1","volume-title":"HIV Surveillance Report, 2018","author":"Centers for Disease Control and Prevention"},{"key":"e_1_2_10_134_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1245"},{"key":"e_1_2_10_135_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-017-2692-2"},{"key":"e_1_2_10_136_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-014-0215-y"},{"key":"e_1_2_10_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2018.02.009"},{"key":"e_1_2_10_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2014.05.003"},{"key":"e_1_2_10_139_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000556"},{"key":"e_1_2_10_140_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir627"},{"key":"e_1_2_10_141_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283354a7b"},{"key":"e_1_2_10_142_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu701"},{"key":"e_1_2_10_143_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt168"},{"key":"e_1_2_10_144_1","volume-title":"HIV Nephropathy","author":"Rivera MJG","year":"2021"},{"key":"e_1_2_10_145_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12567"},{"key":"e_1_2_10_146_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-6-11"},{"key":"e_1_2_10_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2016.11.019"},{"key":"e_1_2_10_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2017.11.009"},{"issue":"8","key":"e_1_2_10_149_1","first-page":"43","article-title":"Assessment of glycemic status, insulin resistance and hypogonadism in HIV infected male patients","volume":"68","author":"Bajaj S","year":"2020","journal-title":"J Assoc Physicians India"},{"key":"e_1_2_10_150_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001348"},{"key":"e_1_2_10_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2010.01886.x"},{"key":"e_1_2_10_152_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijem.IJEM_127_17"},{"key":"e_1_2_10_153_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101210\u20102482"},{"key":"e_1_2_10_154_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijstd.IJSTD_67_17"},{"key":"e_1_2_10_155_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijem.IJEM_694_17"},{"key":"e_1_2_10_156_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1892-5"},{"key":"e_1_2_10_157_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000821"},{"key":"e_1_2_10_158_1","doi-asserted-by":"publisher","DOI":"10.1186\/1742-6405-11-6"},{"issue":"7","key":"e_1_2_10_159_1","first-page":"341","article-title":"HIV\u2010associated hypogonadism","volume":"16","author":"Cohan GR","year":"2006","journal-title":"AIDS Read"},{"key":"e_1_2_10_160_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028512"},{"key":"e_1_2_10_161_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-020-01558-6"},{"key":"e_1_2_10_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.310"},{"key":"e_1_2_10_163_1","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200001010-00016"},{"key":"e_1_2_10_164_1","doi-asserted-by":"publisher","DOI":"10.1086\/497270"},{"key":"e_1_2_10_165_1","doi-asserted-by":"publisher","DOI":"10.1097\/gme.0b013e31824cfc0f"},{"key":"e_1_2_10_166_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-3195"},{"key":"e_1_2_10_167_1","doi-asserted-by":"publisher","DOI":"10.1086\/322695"},{"key":"e_1_2_10_168_1","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2005.19.703"},{"key":"e_1_2_10_169_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.GME.0000141981.88782.38"},{"key":"e_1_2_10_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2055-6640(20)30874-8"},{"key":"e_1_2_10_171_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-2197"},{"key":"e_1_2_10_172_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0b013e31829d4c4c"},{"key":"e_1_2_10_173_1","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000001058"},{"key":"e_1_2_10_174_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001864"},{"key":"e_1_2_10_175_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir628"},{"key":"e_1_2_10_176_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2019.0323"},{"key":"e_1_2_10_177_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357\u2010021\u201000354\u2010w"},{"key":"e_1_2_10_178_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-020-00268-z"},{"key":"e_1_2_10_179_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-017-9776-z"},{"key":"e_1_2_10_180_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.2.869"},{"key":"e_1_2_10_181_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.85.1.60"},{"key":"e_1_2_10_182_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.57.2.141"},{"key":"e_1_2_10_183_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11596-018-1864-7"},{"key":"e_1_2_10_184_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.83.8.5051"},{"key":"e_1_2_10_185_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.1.59"},{"key":"e_1_2_10_186_1","doi-asserted-by":"publisher","DOI":"10.2174\/1570162X13666150121111548"},{"key":"e_1_2_10_187_1","doi-asserted-by":"publisher","DOI":"10.3390\/v12121443"},{"key":"e_1_2_10_188_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02662-18"},{"key":"e_1_2_10_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.09.080"},{"key":"e_1_2_10_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2012.05.016"},{"key":"e_1_2_10_191_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-019-09900-y"},{"key":"e_1_2_10_192_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13365-020-00886-5"},{"key":"e_1_2_10_193_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-91240-0"},{"key":"e_1_2_10_194_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.00894"},{"key":"e_1_2_10_195_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12375"},{"key":"e_1_2_10_196_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(98)00071-7"},{"key":"e_1_2_10_197_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2015.00083"},{"key":"e_1_2_10_198_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.110.178244"},{"key":"e_1_2_10_199_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301261"},{"key":"e_1_2_10_200_1","doi-asserted-by":"publisher","DOI":"10.1002\/trc2.12107"},{"key":"e_1_2_10_201_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-005-0148-7"},{"key":"e_1_2_10_202_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12351"}],"container-title":["Journal of Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.13047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jne.13047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.13047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T22:04:34Z","timestamp":1692828274000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.13047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,14]]},"references-count":201,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1111\/jne.13047"],"URL":"https:\/\/doi.org\/10.1111\/jne.13047","archive":["Portico"],"relation":{},"ISSN":["0953-8194","1365-2826"],"issn-type":[{"value":"0953-8194","type":"print"},{"value":"1365-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,14]]},"assertion":[{"value":"2021-06-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13047"}}