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This paper is structured on a question\u2010answer format in order to also address controversial issues and areas where uncertainty regarding the management and follow\u2010up of aNET exists. All recommendations are offered on the basis of the best available evidence, along with the authors' experiences in managing these neoplasms. Each recommendation for treatment will provide a level of evidence and grade of recommendation as per the GRADE system (adapted in Infectious Disease Society of United States Public Health Service grading system).<\/jats:p>","DOI":"10.1111\/jne.13332","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T12:06:32Z","timestamp":1692187592000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["European Neuroendocrine Tumor Society (\n                    <scp>ENETS<\/scp>\n                    ) 2023 guidance paper for appendiceal neuroendocrine tumours (\n                    <scp>aNET<\/scp>\n                    )"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5876-7883","authenticated-orcid":false,"given":"Gregory","family":"Kaltsas","sequence":"first","affiliation":[{"name":"1st Propaedeutic Department of Internal Medicine National and 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