{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T22:30:40Z","timestamp":1773354640075,"version":"3.50.1"},"reference-count":91,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T00:00:00Z","timestamp":1726531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["RO1NS104008"],"award-info":[{"award-number":["RO1NS104008"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Domestic strains of canaries (\n                    <jats:italic>Serinus canaria<\/jats:italic>\n                    ) variably respond to photoperiod changes and apparently stay in breeding state for extended periods. Fife Fancy canaries are supposed to be similar to the native species living at 27\u201339\u00b0 north where photoperiod significantly changes across the year. Our birds showed reproductive cycles when exposed to light regimes mimicking the annual cycle of photoperiod. However after 6\u2009months in short days (SD: 8L:16D), males developed large testes, as observed by X\u2010ray tomography, and intense singing. Switching to long days (LD: 16L:8D) did not further increase song rate nor testes size but increased song duration, number of syllables per song, and trill occurrence frequency. No sign of regression was observed after 12\u2009weeks in LD but return to SD produced a rapid decrease in testes size and singing activity below values in birds maintained throughout in SD. Fife Fancy thus does not seem to develop absolute but only relative refractoriness. The relatively high singing activity expressed by SD\u2010photosensitive males does not seem to depend on high testosterone (T) concentrations. Singing did not correlate with plasma testosterone (T). Treatment with ATD\u2009+\u2009Flutamide only marginally decreased song rate and did not affect song quality nor song control nuclei volume. These birds are either supersensitive to low T levels or their reproductive physiology is activated by other mechanisms. Neurogenesis is increased by T and by LD but the function of new neurons incorporated in HVC is poorly understood. We developed a procedure based on X\u2010ray focal irradiation to deplete neural progenitors adjacent to HVC and study the functional consequences. The decrease in neurogenesis increased the variability of T\u2010induced songs in females and decreased their bandwidth. Neurogenesis in HVC thus plays a role in song production and X\u2010ray focal irradiation represents an excellent tool to analyze adult neurogenesis.\n                  <\/jats:p>","DOI":"10.1111\/jne.13449","type":"journal-article","created":{"date-parts":[[2024,9,17]],"date-time":"2024-09-17T13:45:55Z","timestamp":1726580755000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Photoperiodism, testosterone and adult neurogenesis in canaries (\n                    <i>Serinus canaria<\/i>\n                    )"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9492-2126","authenticated-orcid":false,"given":"Jacques","family":"Balthazart","sequence":"first","affiliation":[{"name":"GIGA Neurosciences University of Liege  Li\u00e8ge Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,17]]},"reference":[{"key":"e_1_2_15_2_1","first-page":"161","volume-title":"Evolution (Essays Presented to ES Goodrich)","author":"Baker JR","year":"1938"},{"key":"e_1_2_15_3_1","first-page":"1215","article-title":"Role of extreme changes in photoperiod in the annual cycles of birds and insects","volume":"23","author":"Farner DS","year":"1964","journal-title":"Fed Proc"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-919X.1970.tb00096.x"},{"key":"e_1_2_15_5_1","volume-title":"Avian Breeding Cycles","author":"Murton RK","year":"1977"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0970253"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0780267"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1982.0030"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7998.1985.tb04937.x"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1071\/MU9950208"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2008.01.002"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1890\/0012-9658(1998)079[2365:RSIAOB]2.0.CO;2"},{"key":"e_1_2_15_13_1","first-page":"283","volume-title":"Marshall's Physiology of Reproduction","author":"Follett BK","year":"1984"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1988.68.1.133"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/074873001129002079"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195335903.003.0017"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.2649"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-15350-1.00002-2"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-15350-1.00001-0"},{"key":"e_1_2_15_20_1","first-page":"117","article-title":"Breeding biology of the Island canary Serinus canaria (Aves: Fringillidae) on the desertas Island Ilheu Chao","volume":"50","author":"Voigt C","year":"1988","journal-title":"Bol Mus Mun Funchal"},{"key":"e_1_2_15_21_1","volume-title":"Handbook of the Birds of the World","author":"Hoyo J","year":"2010"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1163\/156853901753172700"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-15350-1.00009-5"},{"key":"e_1_2_15_24_1","first-page":"357","article-title":"Behaviour\u2010genetic analysis of canary song: inter\u2010strain differences in sensory learning, and epigenetic rules","volume":"49","author":"Mundinger PC","year":"1995","journal-title":"Anim Behav"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1163\/000579510X489903"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2019.104617"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.0640451"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(76)90101-5"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(77)90192-7"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016-6480(80)90161-6"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jez.a.10245"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2019.112437"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2005.03.074"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2006.03.001"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1006\/gcen.2000.7597"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.0800327"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1530\/jrf.0.1110001"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2022.105194"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2021.113808"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2018.06.004"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1163\/156853998792913500"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-3472(95)90082-9"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.071944"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2008.05.011"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901650405"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(19971105)33:5<602::AID-NEU8>3.0.CO;2-8"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7313697"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90102-X"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1298.006"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1298.043"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2016.03.003"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0030164"},{"key":"e_1_2_15_53_1","first-page":"332","volume-title":"Neuroscience of Birdsong","author":"Brenowitz EA","year":"2008"},{"key":"e_1_2_15_54_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0361-19.2020"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/neu.20268"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2019.104643"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yhbeh.2022.105197"},{"key":"e_1_2_15_58_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.8.2390"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6474166"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902400204"},{"key":"e_1_2_15_61_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-06-01756.1991"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.17.7844"},{"key":"e_1_2_15_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.17.7849"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063692"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.23661"},{"key":"e_1_2_15_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2007.02.002"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2008.06059.x"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0088-11.2011"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2013.10.005"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(199607)30:3<329::AID-NEU2>3.0.CO;2-6"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-09-06281.1995"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4695(199704)32:4<426::AID-NEU6>3.0.CO;2-8"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1006\/frne.2002.0230"},{"key":"e_1_2_15_74_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0553-16.2016"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.1159\/000447048"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80910-1"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.22.8722"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19990830)411:3<487::AID-CNE10>3.0.CO;2-M"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-1047(90)90797-A"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-09-02896.1991"},{"key":"e_1_2_15_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-1047(93)91215-9"},{"key":"e_1_2_15_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/dneu.22180"},{"key":"e_1_2_15_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2006.11.041"},{"key":"e_1_2_15_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.1214"},{"key":"e_1_2_15_85_1","doi-asserted-by":"publisher","DOI":"10.1667\/RR2214.1"},{"key":"e_1_2_15_86_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0007017"},{"key":"e_1_2_15_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-079X.2008.00632.x"},{"key":"e_1_2_15_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.20158"},{"key":"e_1_2_15_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-36089-1"},{"key":"e_1_2_15_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygcen.2014.09.008"},{"key":"e_1_2_15_91_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.17.7854"},{"key":"e_1_2_15_92_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3371-16.2017"}],"container-title":["Journal of Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.13449","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T19:57:39Z","timestamp":1749412659000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.13449"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,17]]},"references-count":91,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/jne.13449"],"URL":"https:\/\/doi.org\/10.1111\/jne.13449","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JNE.13449\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v2\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.13449\/v2\/response1","asserted-by":"object"}]},"ISSN":["0953-8194","1365-2826"],"issn-type":[{"value":"0953-8194","type":"print"},{"value":"1365-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,17]]},"assertion":[{"value":"2024-04-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13449"}}