{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T15:48:35Z","timestamp":1779896915378,"version":"3.53.1"},"reference-count":38,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T00:00:00Z","timestamp":1751760000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T00:00:00Z","timestamp":1751760000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Neuroendocrinology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Endoscopic submucosal dissection (ESD) has been reported as a feasible and effective treatment for Gastric Neuroendocrine Tumors (G\u2010NETs). However, most of the experience comes from retrospective tertiary centers in Eastern Asia. Data coming from western centers are lacking. This is a retrospective study, including patients who underwent endoscopic resection of G\u2010NETs by ESD between 2010 and 2020 in Western Centers. Important clinical variables such as demographic, size, type, presence of lymphovascular invasion or distant metastasis, completeness of the endoscopic resection, recurrence, and procedure\u2010related complications were recorded. Seventy\u2010three ESD procedures on G\u2010NETs from 69 patients from 11 centers were included. Median G\u2010NETs size on endoscopy was 12\u2009mm (IQR 10\u201315). Case mix accounted for 83.6% type 1, 15.1% type 3, and 1.4% type 2. En\u2010bloc resection was possible in 69 procedure 94.5%, R0 resection rate stood at 79.5%. Five patients (7.2%) were referred for additional surgical intervention. One case of perforation was reported (1.4%), treated endoscopically. Three patients (4.4%) had evidence of recurrence during follow\u2010up. ESD is an effective and safe treatment for G\u2010NETs in western centers.<\/jats:p>","DOI":"10.1111\/jne.70064","type":"journal-article","created":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T19:53:52Z","timestamp":1751831632000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Endoscopic submucosal dissection for gastric neuroendocrine neoplasms: A multicenter retrospective study"],"prefix":"10.1111","volume":"37","author":[{"given":"Nikolaos","family":"Lazaridis","sequence":"first","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0222-7706","authenticated-orcid":false,"given":"Alessandro","family":"Rimondi","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocio","family":"Chacchi\u2010Cahuin","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Lemmers","sequence":"additional","affiliation":[{"name":"Erasme Hospital, Department of Gastroenterology, Hepatopancreatology and Digestive Oncology Department HUB (H\u00f4pital Universitaire de Bruxelles), ULB (Universit\u00e9 Libre de Bruxelles)  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Costa","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u2010Maria","family":"Bucalau","sequence":"additional","affiliation":[{"name":"Erasme Hospital, Department of Gastroenterology, Hepatopancreatology and Digestive Oncology Department HUB (H\u00f4pital Universitaire de Bruxelles), ULB (Universit\u00e9 Libre de Bruxelles)  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dalvinder","family":"Mandair","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"},{"name":"Neuroendocrine Tumour Unit, Centre for Gastroenterology, ENETS Centre of Excellence Royal Free London NHS. Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Westmead Hospital, University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcel","family":"Tantau","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology University of Medicine and Pharmacy Iuliu Hatieganu  Cluj\u2010Napoca Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Pioche","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Department Edouard Herriot Hospital  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Rivory","sequence":"additional","affiliation":[{"name":"Gastroenterology and Endoscopy Department Edouard Herriot Hospital  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Santos\u2010Antunes","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Centro Hospitalar S\u00e3o Jo\u00e3o, Faculty of Medicine of the University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margarida","family":"Marques","sequence":"additional","affiliation":[{"name":"Gastroenterology Department Centro Hospitalar S\u00e3o Jo\u00e3o, Faculty of Medicine of the University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0365-1231","authenticated-orcid":false,"given":"Felipe","family":"Ramos Zabala","sequence":"additional","affiliation":[{"name":"Departamento de Gastroenterolog\u00eda, Departamento de Ciencias M\u00e9dicas Cl\u00ednicas Hospital Universitario HM Montepr\u00edncipe, HM Hospitales, Universidad San Pablo\u2010CEU, CEU Universities  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Barbaro","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit Gemelli Hospital  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Pimentel\u2010Nunes","sequence":"additional","affiliation":[{"name":"Department of Surgery and Physiology Faculty of Medicine, University of Porto (FMUP)  Porto Portugal"},{"name":"Unilabs  Porto Portugal"},{"name":"RISE@CI\u2010IPO (Health Research Network), IPO\u2010Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Uchima","sequence":"additional","affiliation":[{"name":"Gastroenterology (GI Endoscopy Unit) Hospital Universitari Germans Trias i Pujol  Badalona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Albeniz","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Endoscopy Unit Complejo Hospitalario de Navarra. Navarrabiomed\u2010UPNA\u2010IdiSNA  Pamplona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Dinis\u2010Ribeiro","sequence":"additional","affiliation":[{"name":"Department of Surgery and Physiology Faculty of Medicine, University of Porto (FMUP)  Porto Portugal"},{"name":"RISE@CI\u2010IPO (Health Research Network), IPO\u2010Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Costamagna","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit Gemelli Hospital  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano","family":"Spada","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit Gemelli Hospital  Roma Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Bourke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Westmead Hospital, University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martyn","family":"Caplin","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"},{"name":"Neuroendocrine Tumour Unit, Centre for Gastroenterology, ENETS Centre of Excellence Royal Free London NHS. Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Toumpanakis","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"},{"name":"Neuroendocrine Tumour Unit, Centre for Gastroenterology, ENETS Centre of Excellence Royal Free London NHS. Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward J.","family":"Despott","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Murino","sequence":"additional","affiliation":[{"name":"Royal Free Unit for Endoscopy The Royal Free Hospital, University College London Institute for Liver and Digestive Health  London UK"},{"name":"Department of Gastroenterology, Digestive Diseases and Surgery Institute Cleveland Clinic London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443168"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPA.0B013E3181EBB168"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jne.13306"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/S41379\u2010018\u20100110\u2010Y"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/HIS.13975"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/JAMAONCOL.2017.0589"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ANNONC.2020.03.304"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2020.02.011"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000457956"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101751\u20105742"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/A\u20101811\u20107025"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.5754\/HGE121185"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/DEN.13778"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/S11605\u2010021\u201004997\u20100"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CGH.2020.06.023"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2019.1588367"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000521654"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.DLD.2021.11.012"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/253860"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl\u20102015\u2010311110"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000335595"},{"key":"e_1_2_8_23_1","volume-title":"WHO Classification of Tumours of the Digestive System","author":"Bosman FT","year":"2010"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12456"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.GIE.2009.10.027"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.GIEC.2014.09.001"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2014.12.010"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2021.11.038"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.giec.2014.09.007"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.GIEC.2014.09.004"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2015.0011"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.4251\/WJGO.V12.I8.791"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12197"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE\u201012\u20100836"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/S12020\u2010017\u20101355\u20109"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.3748\/WJG.V18.I40.5799"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1100\/2012\/869769"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.3748\/WJG.V19.I46.8703"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16020352"}],"container-title":["Journal of Neuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.70064","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/jne.70064","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/jne.70064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T01:20:30Z","timestamp":1771464030000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/jne.70064"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,6]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/jne.70064"],"URL":"https:\/\/doi.org\/10.1111\/jne.70064","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/JNE.70064\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/JNE.70064\/v1\/decision1","asserted-by":"object"}]},"ISSN":["0953-8194","1365-2826"],"issn-type":[{"value":"0953-8194","type":"print"},{"value":"1365-2826","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,6]]},"assertion":[{"value":"2025-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70064"}}